Hydrogel matrices for spheroid encapsulation.

Hydrogel matrices for spheroid encapsulation. (a) Schematic...

Multicellular spheroids made of stem cells can act as building blocks that fuse to capture complex aspects of native in vivo environments, but the effect of ...

Tumor Spheroid Fabrication and Encapsulation in Polyethylene ...

PEG hydrogels are a versatile platform for spheroid encapsulation, as hydrogel ... spheroids to study spheroid growth and various cell-matrix ...

Spatially arranged encapsulation of stem cell spheroids within ...

Hydrogels have been used widely as spheroid-encapsulating materials because of their ECM-like characteristics, including high water content, ...

Corning® Synthegel™ 3D Matrix Kits | Synthetic Hydrogels for 3D ...

It is incredibly easy for cell encapsulation and spheroid isolation. After harvesting, spheroids can be used directly for various downstream tasks such as drug ...

Hydrogel matrix presence and composition influence drug ...

Matrix-encapsulated multicellular spheroids represent such model because they recapitulate solid tumor characteristics, such as dimensionality, ...

Hydrogel viscoelasticity modulates migration and fusion of ...

The area of spheroids encapsulated in SR gels did not undergo a statistically significant increase throughout the 5-day time course despite the ...

Spheroid-Hydrogel-Integrated Biomimetic System: A New Frontier in ...

To overcome these limitations, the combination of spheroids with hybrid systems incorporating matrices such as hydrogels should be considered.

Hydrogels for 3D Cell Culture - Sigma-Aldrich

Among these diverse approaches (scaffold based like hydrogels or rigid scaffolds, scaffold free like low attachment plates or hanging drops for spheroids ...

Structurally and mechanically tuned macroporous hydrogels ... - PNAS

Structurally and mechanically tuned macroporous hydrogels for scalable mesenchymal stem cell–extracellular matrix spheroid production. Sheng Yin ...

Polyglycerol-Based Hydrogel as Versatile Support Matrix for 3D ...

The primary objective for this hydrogel is to maintain a stable and durable crosslinked structure that can securely hold the encapsulated cells within a 3D ...

Hydrogel Matrix Presence and Composition Influences Drug ...

We used a hydrogel-encapsulated GBM spheroid model, where matrix properties were independently altered to investigate their effect on GBM ...

Generation of 3D Spheroids Using a Thiol–Acrylate Hydrogel ...

Heights of the fluidic layer and traps are 100 and 300 μm, respectively, for both the 150 and 300 μm trapping arrays. (D) Protocol of spheroid ...

Tumor Spheroid Fabrication and Encapsulation in Polyethylene ...

PEG hydrogels are a versatile platform for spheroid encapsulation, as hydrogel properties such as stiffness, degradability, and cell ...

3D Spheroid Invasion Assay With the Xeno-free, Bio-Functional ...

VitroGel Hydrogel Matrix supplies the spheroids with multiple binding ligands to facilitate the formation of strong and complex cell-cell and ...

Effect of GelMA Hydrogel Properties on Long-Term Encapsulation ...

The controlled balance between these factors was found to significantly enhance the differentiation and functionality of the encapsulated spheroids. Our results ...

Hydrogel Cell Seeding Encapsulation Protocol - Advanced BioMatrix

... hydrogel; (2) seeding cells on top of the hydrogel ... Matrices for Spheroid and Organoid Culture ... Hydrogel Cell Seeding Encapsulation Protocol ...

3D culture of alginate-hyaluronic acid hydrogel supports the ... - Nature

Hydrogel matrix presence and composition influence drug responses of encapsulated glioblastoma spheroids. Acta Biomater. 132, 437–447 (2021) ...

Efficient fabrication of monodisperse hepatocyte spheroids and ...

Our results showed that hydrogel encapsulation of hepatocyte spheroid promoted hepatic marker expression and secretory functions. In addition, ...

Hydrogel microenvironments for cancer spheroid growth and drug ...

Using hemispherical microwell arrays fabricated in polydimethylsiloxane, MCSs were formed by liver cancer cell line in the alginate hydrogel (91) ...

Generation of uniform-sized multicellular tumor spheroids using ...

found that the spheroid size and functionality could be modulated by the stiffness of the encapsulating hydrogel. Utilizing cell spheroids ...