IL|17–induced HIF1α drives resistance to anti

IL|17–induced HIF1α drives resistance to anti–PD|L1 via fibroblast ...

IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast ...

Increasing evidence suggests that intratumoral inflammation has an outsized influence on antitumor immunity. Here, we report that IL-17, ...

IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast ...

IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion. In Special Collection: JEM Cancer Immunotherapy 2022.

(PDF) IL-17–induced HIF1α drives resistance to anti–PD-L1 via ...

By timing the deletion of IL-17 signaling specifically in cancer-associated fibroblasts (CAFs) in late-stage tumors, we show that IL-17 ...

[PDF] IL-17–induced HIF1α drives resistance to anti–PD-L1 via ...

IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion ... IL-17 promotes collagen deposition by cancer-associated ...

IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast ...

By timing the deletion of IL-17 signaling specifically in cancer-associated fibroblasts (CAFs) in late-stage tumors, we show that IL-17 signaling drives immune ...

IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast ...

Increasing evidence suggests that intratumoral inflammation has an outsized influence on antitumor immunity. Here, we report that IL-17, a proinflammatory ...

IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast ...

Article "IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion" Detailed information of the J-GLOBAL is an ...

IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast ...

Request PDF | On Oct 1, 2024, Yun Liao published IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune ...

The IL-17 family in diseases: from bench to bedside - Nature

... 17RB, IL-17RC, IL-17RD, and IL-17RE. IL ... IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion.

IL-17 Control of Cutaneous Immune Homeostasis - ScienceDirect.com

Liu, et al. IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion. J Exp Med, 219 (2022), Article e20210693. View in ...

Role and functional mechanisms of IL‑17/IL‑17R signaling in ...

... drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion. ... via induction of inflammatory cancer-associated fibroblasts.

The Role of IL-17 in the Pathogenesis of Oral Squamous Cell ... - MDPI

IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion. J. Exp. Med. 2022, 219, e20210693. [Google Scholar] [CrossRef] ...

Evidence for interleukin 17 involvement in severe immune-related ...

... induced specific markers (CD25+) compatible with T-helper 17 ... IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion.

Xiaoxia Li Publications | Ohio Innovation Exchange

A TH17-intrinsic IL-1β–STAT5 axis drives steroid resistance ... IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion.

Blocking IL-17A enhances tumor response to anti-PD-1 ... - OUCI

IL-17A led to high PD-L1 expression in CRC cells through ... IL-17–induced HIF1α drives resistance to anti–PD-L1 via fibroblast-mediated immune exclusion.

IL-17A Orchestrates Reactive Oxygen Species/HIF1α–Mediated ...

Key Points. IL-17A modulates keratinocyte metabolism and proliferation via an ROS–HIF1α axis.Inhibition of the keratinocyte–IL-17A axis ...

Hypoxic microenvironment in cancer: molecular mechanisms and ...

For instance, PD-L1 is secreted by hypoxia-induced HIF-1α, but ... resistance to anti-PD-1 immunotherapy. Nat. Commun. 13, 4118 (2022) ...

Abnormal generation of IL-17A represses tumor infiltration of stem ...

IL-17-induced HIF1alpha drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion. J Exp Med. 2022;219(6):e20210693. CAS ...

Hypoxia Potentiates the Inflammatory Fibroblast Phenotype ...

... anti-PD-L1 therapy in retrospective studies (6, 8). In contrast, iCAFs ... HIF1α mediates the hypoxia-induced inflammatory phenotype in fibroblasts. A ...

Mechanisms of HIF1A-mediated immune evasion in gastric cancer ...

... resistance to anti-PD-1 immunotherapy (Ma et al. 2022). Additionally ... Resistance of hypoxic cells to ionizing radiation is mediated in part via ...