IL|17 Control of Cutaneous Immune Homeostasis

IL-17 Control of Cutaneous Immune Homeostasis - PubMed

IL-17 is widely recognized for its roles in host defense and inflammatory disorders. However, it has become clear that IL-17 is also an ...

IL-17 Control of Cutaneous Immune Homeostasis - ScienceDirect.com

IL-17 is widely recognized for its roles in host defense and inflammatory disorders. However, it has become clear that IL-17 is also an essential regulator ...

IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in ...

Most notably, loss of IL-17 was accompanied by significant reductions in many of the inflammatory mediators found elevated in the WAS−/− skin ( Figure 6D ), to ...

IL-17 Control of Cutaneous Immune Homeostasis | Request PDF

In the absence of UV exposure, probiotic bacteria had no detectable effect on the immune system of the skin, thus acting only to re-establish skin homeostasis.

IL-17 and IL-17-producing cells in protection versus pathology - Nature

IL-17 cytokine family members have diverse biological functions, promoting protective immunity against many pathogens but also driving ...

The IL-17 Family of Cytokines in Health and Disease - Cell Press

immune homeostasis (Fu and ... Interleukin-23 Production from · CD301b+ Dermal Dendritic Cells and Drive Protective Cutaneous Immunity.

Editorial: The IL-17 Cytokine Family in Tissue Homeostasis and ...

The IL-17 cytokines can modulate complex dynamic interactions between stromal and immune cells and determine the outcome of pathophysiological ...

Targeting lymphoid-derived IL-17 signaling to delay skin aging

Mechanistically, aberrant IL-17 signals through NF-κB in epidermal cells to impair homeostatic functions while promoting an inflammatory state.

IL-17A inhibitors alleviate Psoriasis with concomitant restoration of ...

Conclusion: The psoriatic gut/skin microbiota exhibits loss of community stability and pathogen enrichment. IL-17A inhibitors restore microbiota homeostasis and ...

Interleukin-17 cytokines: Effectors and targets in psoriasis—A ...

Those findings highlight the central role of the cytokines IL-17A and IL-17F in establishing skin-commensal homeostasis and in protective immune ...

The IL-17 Family of Cytokines in Health and Disease - Cell Press

γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis ... Non-classical Immunity Controls Microbiota Impact on Skin Immunity and ...

IL-17 and IL-21: Their Immunobiology and Therapeutic Potentials

IL-17 stands as a central orchestrator in the immune system, asserting profound effects on tissue physiology and homeostasis. This cytokine's ...

Dissecting the complexity of γδ T-cell subsets in skin homeostasis ...

Because of the critical role of γδ17 T lymphocytes in psoriasis, several studies aimed to identify different molecules that regulate their ...

Keratinocytes control skin immune homeostasis through de novo ...

Glucocorticoids (GC), synthesized by the 11β-hydroxylase (Cyp11b1), control excessive inflammation through immunosuppressive actions.

IL‐17: Balancing Protective Immunity and Pathogenesis - Sun - 2023

The fundamental role of the epithelium of the gastrointestinal tract and skin, which combined are the largest human body surface area exposed to ...

IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in ...

Our findings reveal a previously unrecognized IL-17-dependent breakdown in immune homeostasis and cutaneous barrier integrity in the absence of ...

the diverse contribution of keratinocytes to immune responses in skin

IL-6 is expressed by human keratinocytes and is reported to be overexpressed in many inflammatory skin diseases, such as psoriasis (79, 86), CLE ...

Control of Regulatory T Cell Migration, Function, and Homeostasis

Indeed, cTregs are particularly dependent on IL-2 for their homeostatic maintenance, whereas eTreg maintenance and proliferation are largely IL- ...

Evolved to protect, designed to destroy: IL‐17‐producing γδ T cells ...

Over the last 10 years, γδ T cells that produce the cytokine IL-17 (γδT17) have taken a leading position in our understanding of how our immune ...

Epigenetic control of skin immunity - Taylor & Francis Online

The skin maintains homeostasis via crosstalk between immune and non-immune cells. Disruption of normal epigenetic regulation in these cells may alter the ...