Identification of Niche|Specific Gene Signatures between Malignant ...

Identification of Niche-Specific Gene Signatures between Malignant ...

In the present study, we proposed a strategy to identify niche-specific gene signatures by harmonizing scRNA-seq and spatial transcriptomic data.

(PDF) Identification of Niche-Specific Gene Signatures between ...

We observed distinct gene signatures specific to cellular niches and their neighboring counterparts. Intriguingly, these niche-specific genes ...

Identification of Niche-Specific Gene Signatures between Malignant ...

We observed distinct gene signatures specific to cellular niches and their neighboring counterparts. Intriguingly, these niche-specific genes display ...

Identification of a gene signature for discriminating metastatic from ...

Understanding the biological factors that are characteristic of metastasis in melanoma remains a key approach to improving treatment.

Identification of Niche-Specific Gene Signatures between ... - Altmetric

Identification of Niche-Specific Gene Signatures between Malignant Tumor Microenvironments by Integrating Single Cell and Spatial ...

Identification of Tissue Specific DNA Methylation Signatures for ...

We detected 373 genomic locations with tissue specific epigenetic patterns in benign and malignant nodules (Table S2). Based on these 373 ...

Identification of Gene Signatures and Expression Patterns During ...

Our discovered signatures may provide an effective and precise transcriptomic reference to monitor EMT progression at the single-cell level.

Spatial transcriptomics reveals niche-specific enrichment ... - Nature

Malignant gliomas, including diffuse midline glioma-H3K27M mutant (DMG) and glioblastoma (GBM), are the most frequent and lethal primary brain ...

Single-cell signatures identify microenvironment factors in tumors ...

We selected three tissues—breast, lung, and brain—for which exemplars were annotated as either derived from normal or cancerous tissue. We ...

De novo gene signature identification from single‐cell RNA‐seq with ...

scHFP effectively models the nuanced features of scRNA‐seq data while identifying highly variable gene signatures, unconstrained by predefined structures such ...

Identification of gene signatures from RNA-seq data using Pareto ...

For validation, we ran PAMR (prediction analysis for microarrays) classifier on the selected best cluster, and assessed the classification ...

Clustering malignant cell states using universally variable genes

In contrast to highly variable genes vulnerable to a specific sample bias, UVGs led to better detection of clusters corresponding to distinct ...

Transcriptome analysis identifies putative multi-gene signature ...

We identified 55 coding and 13 noncoding genes specific for malignant pancreatic head masses. Further shortlisting and validation, however, ...

rna seq - How to identify gene expression signatures from gene ...

One then selects the most up or down regulated genes and defines them as the signature of the group of cells. That's how the gene sets of the ...

An Integrative Model of Cellular States, Plasticity, and Genetics for ...

We hypothesized that the fact that each tumor contains multiple cellular states, but that specific states are enriched in subsets of tumors ( ...

Mining Gene Expression Signature for the Detection of Pre ... - PLOS

The genome-wide association studies revealed pathways commonly over-represented in the transition from immortalized to pre-malignant stage, and under- ...

classifying samples by TCGA signature

... specific gene signature (from Verhaak et al., 2010) using R. The ... genes per class, and identified signature genes for all four subtypes.

classifying samples by TCGA signature - Biostars

I have some RNA-seq samples from multiple glioblastoma tumours that I'm now trying to classify according to a specific gene signature (from ...

Identification of Neighbor-Specific Gene Signatures Between ...

Identification of Neighbor-Specific Gene Signatures Between Malignant and Tumor microenvironments by Integrating Single Cell and Spatial transcriptomics ...

Three-gene signature could identify more malignant cells well in the...

... from publication: Significance of Liver Zonation in Hepatocellular Carcinoma ... In conclusion, AEG-1-C75S mutant exhibited zone-specific differential gene ...