Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

We identified susceptibility loci and genes associated with CRC risk, linking CRC predisposition to steroid hormone, protein synthesis and degradation, ...

Known Genetic factors explain only a small fraction of genetic variation in colorectal cancer (CRC). We conducted a genome-wide association study (GWAS) to ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

We identified 4 loci associated with CRC risk; P values for the most significant variant in each locus ranged from 3.92 × 10−8 to 1.24 × 10−12: 6p21.1 ( ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

BACKGROUND & AIMS: Known genetic factors explain only a small fraction of genetic variation in colorectal cancer (CRC). We conducted a genome-wide association ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

Identification of Susceptibility Loci and Genes for Colorectal. Cancer Risk. Chenjie Zeng,1 Koichi Matsuda,2 Wei-Hua Jia,3 Jiang Chang,4 Sun-Seog Kweon,5,6.

Identification of specific susceptibility loci for the early-onset ...

The incidence of early-onset colorectal cancer (EOCRC; patients < 50 years old) has been rising rapidly, whereas the EOCRC genetic ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

We identified susceptibility loci and genes associated with CRC risk, linking CRC predisposition to steroid hormone, protein synthesis and degradation, and ...

Identification of susceptibility loci for colorectal cancer in a genome ...

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis · Discovery of a new CRC susceptibility SNP · Evaluation of CRC SNPs ...

Genome-wide association study of colorectal cancer identifies six ...

We describe six new susceptibility loci reaching a genome-wide threshold of P<5.0E−08. These findings provide additional insight into the ...

Association analyses identify 31 new risk loci for colorectal cancer ...

Thus, the identified susceptibility SNPs collectively account for approximately 15% of the FRR of CRC that can be explained by common genetic ...

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a ...

Heritable factors contribute to the development of colorectal cancer. Identifying the genetic loci associated with colorectal tumor formation could ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

Background & Aims Known genetic factors explain only a small fraction of genetic variation in colorectal cancer (CRC). We conducted a genome- ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.. Known genetic factors explain only a small fraction of genetic variation in ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

Keyphrases · Susceptibility Loci · Susceptibility Genes · Colorectal Cancer Risk · Risk Variant · Colorectal Cancer · Ryanodine Receptor · Ribosomal Protein · SOCS Box ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

Background & Aims Known genetic factors explain only a small fraction of genetic variation in colorectal cancer (CRC). We conducted a genome-wide ...

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. ... BACKGROUND & AIMS: Heritable factors contribute to the ...

Identification of susceptibility loci for colorectal cancer in a genome ...

We conducted replication of top ranked single nucleotide polymorphisms (SNPs) in additional series totalling 14 037 cases and 15 937 controls, identifying a new ...

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a ...

Identifying the genetic loci associated with colorectal tumor formation could elucidate the mechanisms of pathogenesis. METHODS: We conducted a genome-wide ...

Identification of Susceptibility Loci and Genes for Colorectal Cancer ...

укр Українською. Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. https://doi.org/10.1053/j.gastro.2016.02.076 · Full text. Journal ...

Identifying Novel Susceptibility Genes for Colorectal Cancer Risk ...

Results: We identified 25 genes associated with CRC risk at a Bonferroni-corrected threshold of P < 9.1 × 10–6, including genes in 4 novel loci, PYGL (14q22.1), ...