Identification of a universal antigen epitope of influenza A virus ...

Hemagglutinin is a major surface protein in influenza A virus (IAV), and HA2 is relative conserved among different IAVs.

The identified epitope should be a novel universal target for detection and vaccine design and its ability to generate immune protection ...

Identification of a universal antigen epitope of influenza A virus ...

Identification of a universal antigen epitope of influenza A virus using peptide microarray. Wang, Qiuxia; Sun, Zhihao; Li, Jingzhi; Qin, Tao; Ma, Hongwei ...

Identification of a universal antigen epitope of influenza A virus ...

Abstract and Figures. Background Hemagglutinin is a major surface protein in influenza A virus (IAV), and HA2 is relative conserved among different IAVs. It ...

Identification of a universal antigen epitope of influenza A virus ...

Identification of a universal antigen epitope of influenza A virus using peptide microarray. Language: English; Authors: Wang, Qiuxia1,2,3 (AUTHOR) Sun ...

Additional file 1 of Identification of a universal antigen epitope of ...

The signal-to-noise ratios (SNRs) of binding activity between sera from different subtype influenza A viruses (IAVs) and the other H5 16 peptides (including 1th ...

(PDF) Identification of a Universal Antigen Epitope of Influenza A ...

PDF | Background Hemagglutinin is a major surface protein in influenza A virus (IAV), and HA2 is relative conserved among different IAVs. However,.

Development of a Universal Epitope-Based Influenza Vaccine and ...

The IEDB [15] was used to select immunogenic epitopes from influenza virus. Epitopes were selected from conserved regions of the viral HA, NP ...

A targeted single mutation in influenza A virus universal epitope ...

Enhanced Detection of Antigen-Specific CD4+ T Cells Using. Altered Peptide Flanking Residue Peptide-MHC Class II Multimers. J. Immunol. 195 ...

Additional file 2 of Identification of a universal antigen epitope of ...

Additional file 2 of Identification of a universal antigen epitope of influenza A virus using peptide microarray · Qiuxia Wang · Zhihao Sun · Jingzhi Li · Tao Qin ...

Identification of a universal antigen epitope of influenza A virus ...

Abstract Background Hemagglutinin is a major surface protein in influenza A virus (IAV), and HA2 is relative conserved among different IAVs.

Physical detection of influenza A epitopes identifies a stealth ... - PNAS

Vaccines eliciting immunity against influenza A viruses (IAVs) are currently antibody-based with hemagglutinin-directed antibody titer the only ...

Analysis of the conserved protective epitopes of hemagglutinin on ...

Over the last 15 years, numerous broadly neutralizing antibodies (bnAbs) targeting the HA of influenza A viruses have been isolated from B lymphocytes of human ...

Identification and characterization of epitopes from influenza A virus ...

Five McAbs (H1-13, A1-6, H1-15, A1-10 and H1-17) against the HA protein of H1N1 influenza virus were previously prepared in our laboratory (31).

Towards the knowledge-based design of universal influenza epitope ...

Motivation: Influenza A viral heterogeneity remains a significant threat due to unpredictable antigenic drift in seasonal influenza and antigenic shifts caused ...

Conserved epitopes of influenza A virus inducing protective ...

Unlike T-cells, which recognize linear epitopes presented by MHC molecules, B cells can recognize antigen in its native form. Antibody response ...

A targeted single mutation in influenza A virus universal epitope ...

We observe enhanced protection linked to lung-derived influenza-specific CD4+ and CD8+ T cells prior to re-infection. Structural analysis of the ...

Designing a multi-epitope influenza vaccine: an immunoinformatics ...

In this study, epitopes of B lymphocytes, cytotoxic T lymphocytes, and helper T lymphocytes of HA, NA, NP, and M2 proteins from two strains of Influenza A were ...

Immunogenic epitope prediction to create a universal influenza ...

Hemagglutinin is one of the major surface proteins of influenza virus and is a known target of neutralizing antibodies. Such antibodies can block the adsorption ...

Identification of a universal antigen epitope of influenza A virus ...

Some conserved epitopes also have been identified in HA2 of H5 subtype IAV [19]. In this study, novel conserved epitopes in HA2 of IAV were screened by peptide ...