Identifying gene targets for brain|related traits using transcriptomic ...

Identifying gene targets for brain-related traits using transcriptomic ...

Understanding the difference in genetic regulation of gene expression between brain and blood is important for discovering genes for ...

Identifying gene targets for brain-related traits using ... - PubMed

Our results demonstrate the gain of power in gene discovery for brain-related phenotypes using blood cis-eQTL/mQTL data with large sample sizes.

Identifying gene targets for brain-related traits using transcriptomic ...

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood ; Ting Qi ; Yang Wu ; Jian Zeng ; Futao Zhang ...

(PDF) Identifying gene targets for brain-related traits using ...

Using meta-analyzed brain eQTL/mQTL data ( n = 526 to 1,194), we identify 61 genes and 167 DNA methylation (DNAm) sites associated with 4 brain-related traits ...

Identifying gene targets for brain-related traits using transcriptomic ...

Using meta-analyzed brain cis-eQTL/mQTL data (n = 526 to 1194), we identify 61 genes and 167 DNAm sites associated with four brain-related ...

Identifying gene targets for brain-related traits using transcriptomic ...

Using meta-analyzed brain cis-eQTL/mQTL data (n = 526 to 1194), we identify 61 genes and 167 DNAm sites associated with four brain-related phenotypes, most of ...

Identifying gene targets for brain-related traits using transcriptomic ...

Our results demonstrate the gain of power in gene discovery for brain-related phenotypes using blood cis-eQTL or cis-mQTL data with large sample sizes. List of ...

Identifying gene targets for brain-related traits using transcriptomic ...

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood ; English · Nature Communications · 9 · 1 · 2041-1723.

Identifying gene targets for brain-related traits using transcriptomic ...

Dive into the research topics of 'Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood'. Together they form a ...

Identifying gene targets for brain-related traits using transcriptomic ...

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood · Abstract · List of references · Publications that cite this ...

Brain expression quantitative trait locus and network analyses ...

We used brain-specific gene-co-regulation networks to link GWAS loci and prioritize additional genes for five central nervous system diseases.

Multi-omics analyses of cognitive traits and psychiatric disorders ...

Transcriptome-wide analyses identified 83 genes associated with at least one outcome (PBonferroni < 6.72 × 10−6), with multiple trait colocalization also ...

From genetic associations to genes: methods, applications, and ...

Incorporating GWAS data with biological networks aids in identifying disease-associated genes, even those with weak GWAS signals. Integrative ...

Identifying Alzheimer's genes via brain transcriptome mapping

We propose an innovative two-stage approach to identify genes whose expression profiles are related to diagnosis phenotype via brain transcriptome mapping.

Bayesian genome-wide TWAS with reference transcriptomic data of ...

As a result, we identified 85 significant genes with the prefrontal cortex, 82 significant genes with the cortex, and 76 significant genes with ...

Identifying gene targets for brain-related traits using transcriptomic ...

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood · Qi, T; Wu, Y; Zeng, J; Kähönen, M; Lehtimäki, T (2018) ...

Article Brain-trait-associated variants impact cell-type-specific gene ...

Using colocalization and genetic imputation via transcriptome-wide association, we uncover cell-type-specific regulatory mechanisms underlying risk for brain- ...

Gene Target Identification in Complex Disease Research - Illumina

... gene expression, and regulation, or it may have no effect at all. Using genomic, transcriptomic, and epigenomic methods for quantitative trait loci (QTL) ...

Identifying gene targets for brain-related traits using transcriptomic ...

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nat. Commun. Pub Date : 2018-06-11

Article A transcriptomic atlas of the human brain reveals genetically ...

By linking neuroimaging-derived phenotypes with expression levels of specific genes, this resource represents a powerful gene prioritization schema that can ...