Immune Responses to Respiratory Syncytial Virus Vaccines

Immune Responses to Respiratory Syncytial Virus Vaccines - MDPI

During the development a vaccine against RSV, there have been different obstacles, such as concerns about increased respiratory disease after vaccination, which ...

The innate immune response to RSV: Advances in our ...

Both the innate and the adaptive immune responses contribute to the control of RSV infection, but despite successful viral clearance, protective immunity ...

Respiratory Syncytial Virus Infection: Immune Response ...

The most widely accepted explanation for this immune system-mediated enhancement of RSV disease is that there is an imbalance in the Th1- and Th2-lymphocyte ...

Vaccines for Older Adults | RSV - CDC

These vaccines work by causing an immune response that can protect you from respiratory disease if you get RSV in the future. Eligible ...

Immunopathogenesis of vaccine-enhanced RSV disease

Inducing a strong immune response is an essential aim of vaccination. Although immune responses to virus infections are usually protective, they can also be ...

The road to approved vaccines for respiratory syncytial virus - Nature

RSV infection does not generate durable immunity against reinfection, similar to what is seen for other respiratory viruses. Responses to ...

What have we learned from animal studies of immune responses to ...

The immune response to RSV and the mechanisms by which the virus prevents the establishment of immunological memory have been extensively ...

Immunity towards human respiratory syncytial virus

The innate immune response has a crucial role during hRSV infection. Its modulation has been widely demonstrated by hRSV in which activation of ...

Mucosal immunization with a low-energy electron inactivated ...

RSV is a respiratory virus infecting the airway mucosa, and therefore an immune response directly at the site of infection may be beneficial (7, ...

RSV Immunity, Durability, and Reinfection - FDA

The human immune response to respiratory syncytial virus infection. Clin Microbiol Rev 30:481–502. Russell CD, Unger SA, Walton M, Schwarze J.

Current Insights in the Development of Efficacious Vaccines Against ...

In conclusion a vaccine against RSV that promotes an effective antiviral response must induce a prolonged neutralizing antibody response, Th-1 polarized ...

Immune response to respiratory syncytial virus infection ...

During RSV infection, diverse immune cells such as dendritic cells, macrophages, T cells, B cells and eosinophils are involved in the antiviral response.

The Human Immune Response to Respiratory Syncytial Virus Infection

RSV infection elicits a strong systemic and especially respiratory tract neutrophil response (1–4). Neutrophils are the predominant cell type in ...

Cell-mediated immune responses to respiratory syncytial virus ...

The corollary of this observation is that robust Th1 and/or low Th9, Th22, and TNFα inflammatory responses may be associated with efficient clearance of RSV ...

Human respiratory syncytial virus: pathogenesis, immune responses ...

Induction of high neutralizing antibody responses by pre-F immunization in animal models promoted it as a major vaccine candidate. Since RSV ...

Protective T cell immunity against respiratory syncytial virus ... - PNAS

Our results support the notion that vaccination with BCG expressing RSV antigens induces a Th1 immune response, which protects against RSV ...

Immunogenicity and Safety Following 1 Dose of AS01E-Adjuvanted ...

Respiratory syncytial virus (RSV) is a major cause of illness and hospitalization in older adults. An RSV vaccine for older adults developed by ...

The CD4 T cell response to respiratory syncytial virus infection

This would suggest that the FI-RSV immunization either altered the immune response or enhanced viral replication that led to increased disease ...

Passively Acquired Antibodies Suppress Humoral But Not Cell ...

In experimental animals, passive transfer of RSV Abs decreased the frequency and magnitude of the Ab response to F and G proteins expressed by vaccinia virus ...

Protective And Disease-Enhancing Immune Responses To ...

The fact that neither the disease-enhancing nor the protective immune response to RSV is well understood or well characterized is an important barrier to ...