Immune System Genomics
Immune System Genomics | Broad Institute
Genomic characterization of healthy human cohorts. How human genetics impacts immunity in an individual is a central question in modern immunology. We have ...
The Immunological Genome Project (ImmGen) is a collaborative group of immunology and computational biology labs who join forces and expertise to perform a ...
Genomics and the immune system - PMC - PubMed Central
Within the immune system, it is known that multiple proximal and distal DNA cis-regulatory domains, such as promoters, enhancers, silencers, locus control ...
Human immune diversity: from evolution to modernity - Nature
The immune system possesses immense individual-to-individual diversity. Immunity is intrinsically variable, because it is controlled by the most ...
The immune system and genetics | Immune Deficiency Foundation
Primary immunodeficiencies can be inherited in one of three different ways depending on the specific disorder: X-linked recessive, autosomal recessive, or ...
Immunogenomics - Icahn School of Medicine at Mount Sinai
Laboratory, computational and clinical scientists at the Department of Genetics and Genomic Sciences (GGS) are working together to determine the genetic ...
Immunogenomics | NGS in immune repertoire & autoimmunity studies
Immune-Related Genetic Variation ... Genomic analysis technologies can advance immunology research by elucidating immune cell function and signaling. The causes ...
Genomics of immune diseases and new therapies - PMC
Genomics is the investigation of nucleotide sequence variants in the entire nuclear DNA content of an organism and their effect on phenotype. Up until recently, ...
The dynamic interface of genetics and immunity - Nature
Understanding the genetic basis of immunological processes and their overall dynamics under the influence of population immunogenetics and ...
Immunity and lifespan: answering long-standing questions with ...
We propose that comparative immunogenomics offers a solution to the problem of estimating past selection on immune genes. Specifically, long-read sequencing ( ...
Re-Engineering the Human Immune System - Gladstone Institutes
Researchers harness the power of CRISPR to alter DNA across the genome and discover specific areas that control critical immune cell functions.
Genomics, Genetics, and Genes of the Immune System - Cell Press
To understand immune function comprehensively, we will ultimately need to generate a complete list of proteins that function in immune cells. Conveniently and ...
Using paleogenomics to elucidate 10,000 years of immune system ...
Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10000 years ...
Genomics of infection and immunity - BioMed Central
The issue captures recent advances made using genomic approaches toward understanding the function and diversity of the immune system, regulation of the immune ...
The Gladstone-UCSF Institute of Genomic Immunology blends the latest genomics and genome-engineering technologies with immunology research to engineer the ...
Genetics and Immune Disorders - Health Encyclopedia
Genes also affect the way the immune system works or how it responds to threats. Primary immunodeficiency disorders are present at birth. They are often ...
New insights into human immunity from ancient genomics
We will focus on some recently studied forms of human adaptation to infectious agents, including hybridization with now-extinct hominins, such as Neanderthals ...
Genetics and immunity in the era of single-cell genomics
Immunology is one of the fields that is benefiting the most from such advancements, providing us with completely new insights into mammalian immunity. In this ...
Genomic Views of the Immune System* | Annual Reviews
Genomic-scale experimentation aims to view biological processes as a whole, yet with molecular precision. Using massively parallel DNA ...
Researchers identify over 140 genes linked to immune system ...
They found more than 140 genes involved in controlling the number or activity of immune cells, or the response to infection by pathogens including salmonella ...