- Immune profiling|based targeting of pathogenic T cells with ...🔍
- Immune pro ling|based targeting of pathogenic T cells with ...🔍
- Targeting pro|inflammatory T cells as a novel therapeutic approach ...🔍
- T Cell Immunity to Bacterial Pathogens🔍
- Regulation of T|Cell Immune Responses by Pro|Resolving Lipid ...🔍
- Single|cell transcriptomics identifies pathogenic T|helper 17.1 cells ...🔍
- Principles and therapeutic applications of adaptive immunity🔍
- Therapeutic potential of chimeric antigen receptor based therapies ...🔍
Immune pro ling|based targeting of pathogenic T cells with ...
Immune profiling-based targeting of pathogenic T cells with ... - Nature
We treat four ANCA-GN patients with ustekinumab, which specifically targets Th1 and Th17 cells, as add-on therapy.
Immune profiling-based targeting of pathogenic T cells with ...
Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis. Nat Commun. 2024 Sep 19;15(1):8220. doi: ...
Our ndings suggest that immune-pro ling-based targeting of pathogenic T cells in ANCA-GN patients with ustekinumab is a promising approach ...
(PDF) Immune profiling-based targeting of pathogenic T cells with ...
Our findings thus suggest that targeting of pathogenic T cells in ANCA-GN patients with ustekinumab might represent a potential approach and ...
Targeting pro-inflammatory T cells as a novel therapeutic approach ...
Targeting these cells could inhibit T-cell responses ex vivo. We then dissected one of its working mechanisms by which FcγR-binding anti-PD-1 ...
T Cell Immunity to Bacterial Pathogens - PubMed Central
In the adaptive immune system, major histocompatibility complex (MHC)-restricted αβ T cells, along with unconventional αβ or γδ T cells, respond to bacterial ...
Regulation of T-Cell Immune Responses by Pro-Resolving Lipid ...
These data suggest an increased T-cell sensitivity to pro-inflammatory LTB4 and a critical role of BLT1 in T-cell recruitment into target organs as evidenced in ...
Single-cell transcriptomics identifies pathogenic T-helper 17.1 cells ...
The CD4+ T-cell compartment showed an increase of pathogenic T-helper 17.1 cells, characterized by high co-expression of TBX21 (encoding T-bet) and RORC (ROR-γ) ...
Principles and therapeutic applications of adaptive immunity: Cell
These effects are mediated by lymphocytes that sense and respond with targeted precision to perturbations induced by pathogens and tissue damage ...
Therapeutic potential of chimeric antigen receptor based therapies ...
... targeting immune cells or rebalancing the pro-inflammatory milieu. Important ... to eliminate the pathogenic immune cells or rebalance the inflammatory ...
Targeting the CD40-CD40L pathway in autoimmune diseases
... cells to autoimmune disease pathogenesis. Additionally, novel ... Upon ligation with CD40L, these cells produce pro-inflammatory ...
Interleukin-1 as Innate Mediator of T Cell Immunity - Frontiers
During pathogen infection, signaling via the IL-1R complex can serve as a surrogate for PAMP recognition, which enables effector T cell responses by activating ...
Single-cell transcriptomics identifies pathogenic T-helper 17.1 cells ...
Background Immune checkpoint inhibitor (ICI)- related pneumonitis is the most frequent fatal immune- related adverse event associated with ...
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development, interpreting coronavirus disease 2019 (COVID-19) pathogenesis, ...
CD8+ T cells are also able to use small signalling proteins, known as cytokines, to recruit other types of cells when mounting an immune response. A different ...
COVID‐19 immunopathology with emphasis on Th17 response and ...
These anti-inflammatory cytokines can confine the inflammatory storm caused by immune cells during a virus infection, and suppress multiple ...
An introduction to immunology and immunopathology
T reg cells may also help in the resolution of normal immune responses, as pathogens or antigens are eliminated. These cells also play a ...
Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious ...
Interleukins are produced by different immune cells such as B cells, T cells, dendritic cells, and macrophages. These immune molecules act on different target ...
T cell immunity: What is it and how does it help to protect us from ...
They can act as “killer cells”, attacking cells which have been infected with a virus or another kind of pathogen, or they can act as “helper ...
Th cells recognize and bind to a pathogenic antigen, leading to the release of soluble factors (cytokines) that signal to the rest of the immune ...