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Immune profiling|based targeting of pathogenic T cells with ...


Immune profiling-based targeting of pathogenic T cells with ... - Nature

We treat four ANCA-GN patients with ustekinumab, which specifically targets Th1 and Th17 cells, as add-on therapy.

Immune profiling-based targeting of pathogenic T cells with ...

Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis. Nat Commun. 2024 Sep 19;15(1):8220. doi: ...

Immune pro ling-based targeting of pathogenic T cells with ...

Our ndings suggest that immune-pro ling-based targeting of pathogenic T cells in ANCA-GN patients with ustekinumab is a promising approach ...

(PDF) Immune profiling-based targeting of pathogenic T cells with ...

Our findings thus suggest that targeting of pathogenic T cells in ANCA-GN patients with ustekinumab might represent a potential approach and ...

Immune profiling-based targeting of pathogenic T cells with ...

It is suggested that targeting of pathogenic T cells in ANCA-GN patients with ustekinumab might represent a potential approach and warrants further ...

Immune profiling-based targeting of pathogenic T cells with... - CiteAb

6 reagents referenced in Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis.

Immune Profiling-Based Targeting of Pathogenic T Cells with ...

Immune Profiling-Based Targeting of Pathogenic T Cells with Ustekinumab in ANCA-Associated Glomerulonephritis: SA-PO756 · October 2024 · Journal ...

Katalin Susztak on X: "Immune profiling-based targeting of ...

Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis | @NatureComms ...

Immune profiling-based targeting of pathogenic T cells with ... - CoLab

AbstractAntineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a life-threatening autoimmune disease that often results in kidney failure ...

In-depth immune profiling reveals advanced B- and T-cell ...

Unbiased clustering of T cell mass cytometry data correlated with CVID-related immune dysregulation and plasma protein profiles. Expanded CXCR3+ T-bet- ...

Targeting pathogenic CD8+ tissue-resident T cells with chimeric ...

Liver CD8+ Trm cells also upregulate the expression of several immune checkpoint molecules, including PD-1. We describe the development of a ...

Immune-based, multifaceted inactivation of pathogenic T ...

Immunotherapeutic treatment of autoimmune diseases should aim to inactivate autoaggressive memory T-cells and restore immune tolerance.

Hitting the target: how T cells detect and eliminate tumors - PMC

... profiling have produced insights into the specific targets of anti-tumor T cells ... immunity, which has primarily evolved in response to foreign pathogens.

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...

Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development, interpreting coronavirus disease 2019 (COVID-19) pathogenesis, ...

Immune profiling - Takara Bio

Immune profiling involves the analysis of T- and B-cell receptors (TCRs/BCRs), which allow cells to bind specific antigens, proliferate, and then rapidly ...

CAR T Cells: Engineering Immune Cells to Treat Cancer - NCI

The CAR T-cell therapies approved by FDA to date target one of two antigens on B cells, CD19 or BCMA. Making a CAR T Cell. A growing number of ...

Single-cell immune profiling reveals functional diversity of T cells in ...

Granzyme K–expressing CD8 T cells were preferentially enriched and clonally expanded in pleural fluid from TPE, suggesting that they are ...

Review article Role of T cells in cancer immunotherapy

This review addresses all the strategies targeting tumor pathogenesis, including metabolic pathways, to evaluate the clinical significance of current and ...

Single-cell transcriptomics identifies pathogenic T-helper 17.1 cells ...

The CD4+ T-cell compartment showed an increase of pathogenic T-helper 17.1 cells, characterized by high co-expression of TBX21 (encoding T-bet) and RORC (ROR-γ) ...

Tumor-infiltrating γδ T lymphocytes: pathogenic role, clinical ...

T cells carrying the γδ T cell receptor (TCR) are important effector cells that may play a role in the anti-tumor immune response. γδ Cells are not a ...