Immuno|proteomic profiling reveals abundant airway CD8 T cells ...

Immuno-proteomic profiling reveals aberrant immune cell regulation ...

... abundant proteins and the airway immune cell proportions showed that ... T cells, primarily CD8 Trm cells, and with heightened respiratory dysfunction.

Immuno-proteomic profiling reveals abundant airway CD8 T cells ...

These data indicate that COVID-19 results in a prolonged change to the airway immune landscape in those with persistent lung disease.

Immuno-proteomic profiling reveals abundant airway CD8 T cells ...

Immuno-proteomic profiling reveals abundant airway CD8 T cells and ongoing epithelial injury in prolonged post-COVID19 respiratory disease.

Immuno-proteomic profiling reveals aberrant immune cell regulation ...

Some patients hospitalized with acute COVID-19 suffer respiratory symptoms that persist for many months. We delineated the immune-proteomic ...

(PDF) Immuno-proteomic profiling reveals aberrant immune cell ...

Increased airway T cell and B cell abundance is associated with more severe ongoing respiratory pathophysiology post-COVID-19 (A) Immune cell proportions in ...

Immuno-proteomic profiling reveals aberrant immune cell regulation ...

(2021), Immuno-proteomic profiling reveals abundant airway CD8 T cells and ongoing epithelial injury in prolonged post-COVID19 respiratory ...

Integrative temporal multi-omics reveals uncoupling of transcriptome ...

We report an integrative temporal proteomic and transcriptomic analysis of primary human CD4 and CD8 T cells following ex vivo stimulation with anti-CD3/CD28 ...

Profiling CD8+ T cell epitopes of COVID-19 convalescents reveals ...

The sorted cells were sequenced to quantitate the abundance of the epitopes expressed in the IFP-positive population. Further analysis takes ...

Longitudinal proteomic profiling of T cell differentiation in vivo ...

Longitudinal proteomic profiling of antigen-specific CD8 T cells reveals significant. 89 modulation of the proteome upon activation followed ...

Long COVID manifests with T cell dysregulation, inflammation and ...

Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, yet its etiology ...

Longitudinal analysis of the lung proteome reveals persistent repair ...

... airway T cell frequency in patients with chronic respiratory disease. ... T and NKCD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation.

Proteomic analysis of circulating immune cells identifies cellular ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to present a public health crisis due to a slow global rollout of ...

Single-cell analysis of bronchoalveolar cells in inflammatory and ...

Results: CD4 central memory T cells and CD8 effector memory T cells were significantly more abundant in those with inflammatory radiology. Clustering of ...

Longitudinal proteomic profiling of T cell differentiation in vivo ...

(G) Volcano plot of differential protein abundance in CD8 T cells ... More importantly, our protein abundance profiling of TEX revealed ...

Distinct cellular immune profiles in the airways and blood of critically ...

... shows a relative higher abundance of CD8 T cells in BALF. To gain insight in immune cell migration and the peripheral immune system versus pulmonary, PBMC ...

Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection ...

Deeper profiling of these NK-like T cells reveals heterogeneity within this population and substantial phenotypic differences between mild and severe disease.

Proteomic profiling of lung immune cells reveals dysregulation of ...

Increased intraepithelial (CD103+) CD8+ T cells in the airways of smokers with and without chronic obstructive pulmonary disease. Immunobiology.

Label-free Analysis of CD8+ T Cell Subset Proteomes Supports a ...

Human-Virus-Specific T Cells. Graphical Abstract. Highlights d. MS reveals a clear proteomic hierarchy for circulatory CD8+. T cell subsets d.

T cell phenotypes in COVID-19 - a living review - Oxford Academic

In the airways of moderately severe COVID-19 patients, CD8+ T cells display an anti-viral phenotype, with high expression of CCL5 and cytotoxic ...

T cell immunobiology and cytokine storm of COVID‐19

2019 coronavirus disease (COVID-19) presents as a newly recognized pneumonia and could rapidly progress into acute respiratory distress ...