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Impact of CO2/HCO3– Availability on Anaplerotic Flux in Pyruvate ...

Impact of CO2/HCO3– Availability on Anaplerotic Flux in Pyruvate ...

Impact of CO2/HCO3– Availability on Anaplerotic Flux in Pyruvate ...

As products of decarboxylating reactions and substrates for carboxylation, CO2 and HCO3– are involved in various metabolic processes. Consequently, the ...

Impact of CO 2 /HCO 3 - Availability on Anaplerotic Flux in Pyruvate ...

Remarkably, all measures leading to enhanced CO2/HCO3- levels, such as external addition of HCO3-, increasing the pH, or rerouting metabolic ...

Impact of CO2/HCO3– Availability on Anaplerotic Flux in Pyruvate ...

CO2 is a ubiquitous product of cellular metabolism and an essential substrate for carboxylation reactions. The pyruvate dehydrogenase complex (PDHC) ...

The impact of CO2/HCO3- availability on anaplerotic flux in PDHC ...

The pyruvate dehydrogenase complex (PDHC) catalyzes the oxidative. 19 decarboxylation of pyruvate yielding acetyl-CoA and CO2. The PDHC ...

The impact of CO 2 /HCO 3 - availability on anaplerotic flux in PDHC ...

The pyruvate dehydrogenase complex (PDHC) catalyzes the oxidative decarboxylation of pyruvate, yielding acetyl coenzyme A (acetyl-CoA) and CO2. The PDHC- ...

The impact of CO 2 /HCO 3 - availability on anaplerotic flux in PDHC ...

Remarkably, all measures leading to enhanced CO 2 /HCO 3 ⁻ levels, such as external addition of HCO 3 ⁻ , increasing the pH, or rerouting metabolic flux via ...

levels on metabolism and regulation in Corynebacterium glutamicum

(2001), PYC dominates anaplerotic flux under non-gluconeogenic conditions. Additionally, C. glutamicum is able to decarboxylate pyruvate to acetyl-CoA via ...

Increased availability of HCO3– improved anaplerotic flux via ...

... impact of CO 2 /HCO 3 - availability on anaplerotic flux in PDHC-deficient Corynebacterium glutamicum strains | CO 2 is a ubiquitous product of cellular ...

The impact of CO2/HCO3- availability on anaplerotic flux in PDHC ...

The pyruvate dehydrogenase complex (PDHC) catalyzes the oxidative decarboxylation of pyruvate yielding acetyl-CoA and CO2.

Effect of elevated dissolved carbon dioxide concentrations on ...

Impact of CO2/HCO3– Availability on Anaplerotic Flux in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains · Biology, Environmental ...

Effect of elevated dissolved carbon dioxide concentrations on ...

The carbon flux through the central metabolic pathways and its importance for growth rate and product formation has been widely investigated over the last 20 ...

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant ...

LPCKO mice have impaired hepatic anaplerosis, diminution of TCA cycle intermediates, suppressed gluconeogenesis, reduced TCA cycle flux, and a ...

Reviews and syntheses: Heterotrophic fixation of inorganic carbon

Heterotrophic CO2 fixation is a significant yet un- derappreciated CO2 flux in environmental carbon cycling. ... concurrent anaplerotic CO2 ...

Regulation of pyruvate metabolism and human disease

Under the second, PC provides a critical anaplerotic shunt to maintain citric acid cycle carbon flux. The combined regulation of PC and PDH ...

Flux through hepatic pyruvate carboxylase and ... - PNAS

of anaplerotic pyruvate carboxylase activity and incomplete equil- ibration with fumarate. Hyperpolarized [13C]bicarbonate was also detected ...

CO2 /HCO3 - ASM Journals

... flux via the anaplerotic reactions (28–30). Anaerobic growth on glucose and tryptone could be enhanced by increasing concen- trations of CO2.

Comparative 13C metabolic flux analysis of pyruvate ... - EurekaMag

2019: Impact of CO2/HCO3- Availability on Anaplerotic Flux in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains Journal of ...

(PDF) Impact of different CO2/HCO3− levels on metabolism and ...

(2001), PYC dominates anaplerotic flux under non-gluconeogenic conditions. Additionally, C. glutamicum is able to decarboxylate pyruvate to acetyl-CoA via ...

Elevated Brain Glutamate Levels in Bipolar Disorder and Pyruvate ...

carboxylase employs pyruvate and the polar molecule bicarbonate instead of CO2 ... not increase pyruvate carboxylase-mediated anaplerotic flux ...

Two-Carbon Compounds and Fatty Acids as Carbon Sources

Impact of CO2/HCO3– Availability on Anaplerotic Flux in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains · Aileen KrügerJ. Wiechert ...