Impact of allocation concealment on conclusion drawn from meta ...

Impact of allocation concealment on conclusions drawn from meta ...

Two-thirds of conclusions in favour of one of the interventions were no longer supported if only trials with adequate allocation concealment were included.

Impact of allocation concealment on conclusions drawn from meta ...

Eligible reviews presented a binary effect estimate from a meta-analysis of randomized controlled trials as the first statistically significant ...

Impact of allocation concealment on conclusion drawn from meta ...

Randomized trials without reported adequate allocation concealment have been shown to overestimate the benefit of experimental interventions.

Impact of allocation concealment on conclusions drawn from meta ...

... Randomised clinical trials with certain methodological aws carry an increased risk of bias (69) (70) (71)(72)(73)(74). Such methodological aws increase the ...

Influence of allocation concealment and intention-to-treat analysis ...

This means that the conclusions of meta-analyses are likely to change if restricted to trials with adequate allocation concealment. It has been ...

Different methods of allocation to groups in randomized trials are ...

Inadequate concealment of allocation can lead to exaggeration of treatment effects in randomized controlled trials. Many methods of allocation to groups are ...

Impact of allocation concealment on conclusions drawn from meta ...

Randomized trials without reported adequate allocation concealment have been shown to overestimate the benefit of experimental interventions ...

How often do positive conclusions drawn from meta-analyses ...

Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials. International Journal of Epidemiology 2007;36(4):847-57. CMR ...

Effects of allocation concealment and blinding in trials addressing ...

Blinding of participants and healthcare providers reduces opportunity for differences in care (co-interventions) whereas blinding of outcome ...

What is the influence of randomisation sequence generation and ...

Conclusions. Trials with inappropriate concealment of allocation had an overestimation of treatment effects when compared with trials with adequate concealment ...

Impact of allocation concealment on conclusions drawn from meta ...

Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials · Mentioned by · Citations · Readers on.

Impact of Allocation Concealment and Blinding in Trials Addressing ...

We found that, compared with trials with allocation concealment, trials without allocation concealment may estimate treatments to be more beneficial for ...

Mechanisms and direction of allocation bias in randomised clinical ...

Inadequate allocation concealment may exaggerate treatment effects in some trials while underestimate effects in others. Our hypothesis provides ...

Association of Funding and Conclusions in Randomized Drug Trials

To examine the impact of trial quality, the meta-analyses had to include at least 1 trial with and 1 trial without adequate allocation concealment. Our ...

[PDF] Small study effects in meta-analyses of osteoarthritis trials

Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials. · Medicine. International Journal of Epidemiology · 2007.

Impact of allocation concealment on conclusions drawn from meta ...

Pildal, J., Hrobjartsson, A., Jørgensen, K. J., Hilden, J., Altman, D. G., & Gotzsche, P. C. (2007). Impact of allocation concealment on conclusions drawn from ...

Chapter 10: Analysing data and undertaking meta-analyses

Here, allocation sequence concealment, being either adequate or ... A basic introduction to fixed-effect and random-effects models for meta-analysis.

A meta-epidemiological study to examine the association between ...

Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials. ... effect and the conclusion that benefit is limited to ...

Trial-level characteristics associate with treatment effect estimates

Associations between high or unclear risk of bias on allocation concealment (5/6 for binary outcome and 1/3 for continuous outcome), double ...

The importance of allocation concealment and patient blinding in ...

Effect sizes tended to be less beneficial in 46 trials with adequate allocation concealment compared with 112 trials with inadequate or unclear ...