Improving laboratory diagnosis of von Willebrand Disease

Laboratory diagnosis of von Willebrand disease - PMC

Laboratory diagnosis requires a series of assays of von Willebrand factor (VWF) quantity and function, and factor VIII activity, with no single straightforward ...

Laboratory diagnosis of von Willebrand disease in the age of the ...

VWF:GPIbR assays, being performed on automated platforms, should have lower assay variability and better low VWF level sensitivity than VWF:RCo ...

Laboratory Diagnosis of von Willebrand Disease

These most often include an assessment of von Willebrand factor (VWF) activity and antigen levels, along with coagulation FVIII activity levels. The combination ...

Diagnostic approach to von Willebrand disease | Blood

Once the diagnosis of VWD type 1 is made based on clinical history and laboratory testing, no further specialized testing is usually required.

Diagnosis and Management of Von Willebrand Disease - AAFP

Persons with levels of 30 to 50 IU per dL may not have the disease, but may need agents to increase von Willebrand factor levels during invasive ...

Current issues in diagnosis and treatment of von Willebrand disease

Regardless of these laboratory complexities, clinicians can empirically treat VWD to alleviate bleeding symptoms by raising VWF levels through desmopressin or ...

Improving laboratory diagnosis of von Willebrand Disease

The complexity and heterogeneity of VWF, (pre)analytical variables, limited repertoire of laboratory tests, intra-individual variation, complex ...

Outgrowing the Laboratory Diagnosis of Type 1 Von Willebrand's ...

Introduction: In the general population, von Willebrand factor (VWF) and factor VIII (FVIII) levels are known to increase with age.

A need to increase von Willebrand disease awareness: vwdtest.com

Whenever a patient's bleeding score supports the suspicion of a bleeding disorder, detailed laboratory testing of the patient's coagulation activity under the ...

von Willebrand Disease Workup - Medscape Reference

Currently, many hemostasis laboratories offer these tests. However, the differentiation of vWD as type 1, 2A, 2B, 2M, 2N or 3 must be done ...

Recommendations for the laboratory diagnosis of von Willebrand ...

Von Willebrand disease (vWD) is the most common inherited bleeding disorder; laboratory diagnosis requires a number of assays with no single ...

Reference ranges for von Willebrand factor multimer distribution

However, addition of VWF:CB and multimeric results to the basic laboratory tests, led to an increase in the concordance (79% and 88% for H5/11VWM and in‐house ...

Laboratory diagnosis of von Willebrand disease

Among patients with suspected von Willebrand disease, the laboratory diagnosis requires three levels of testing: screening tests, specific assays for von ...

Clinical presentation and diagnosis of von Willebrand disease

Outline · Baseline hemostasis assessment · VWD initial testing · - VWF antigen · Repeat testing in individuals with borderline or discordant ...

Laboratory Diagnosis of von Willebrand's Disease

In patients with variant forms of vWD, however, multimeric analysis of both platelet and plasma von Willebrand factor may be necessary. Furthermore, more than ...

Von Willebrand Disease - VWD | Choose the Right Test

Although no single laboratory test can be used to diagnose VWD, the initial panel of tests typically includes VWF antigen, VWF factor activity.

Canine von Willebrand Disease

Laboratory diagnosis of VWD is most often based on results of von Willebrand factor antigen assay (abbreviated VWF:Ag). This test measures the amount or ...

Guideline for laboratory diagnosis and monitoring of von Willebrand ...

This guideline describes laboratory tests used to diagnose and monitor individuals with von Willebrand disease (VWD).

Challenges in the laboratory diagnosis and management of von ...

Background: South African von Willebrand disease (VWD) care is challenged by the lack of laboratory testing standardisation, lack of national ...

Laboratory diagnosis of von Willebrand's disorder - ResearchGate

We conclude that laboratories are generally proficient in tests for VWD, and that diagnostic error rates are reduced when test panels are more ...