- In|vitro models of disc degeneration🔍
- In|vitro models of disc degeneration – A review of methods and ...🔍
- In|vitro models of disc degeneration – A review of🔍
- Intervertebral disc degeneration🔍
- In|vitro models of disc degeneration – A review of methods ...🔍
- Intervertebral disc degeneration—Current therapeutic options and ...🔍
- Full article🔍
- In vivo Mouse Intervertebral Disc Degeneration Models and Their ...🔍
In|vitro models of disc degeneration – A review of methods ...
In-vitro models of disc degeneration - A review of methods ... - PubMed
The intervertebral disc (IVD) provides flexibility, acts as a shock absorber, and transmits load. Degeneration of the IVD includes alterations in the ...
In-vitro models of disc degeneration – A review of methods and ...
This review documents in-vitro models of IVD degeneration including physical disruption, hyperphysiological loading, ECM degradation by enzyme digestion, or a ...
In-vitro models of disc degeneration – A review of
The review includes the methods used to. 11 compile and assess ... In-vitro models of disc degeneration may adopt mechanical, biochemical, or hybrid methods.
In-vitro models of disc degeneration – A review of methods and ...
To understand the pathogenesis of IVD degeneration and suitable testing methods for emerging treatments and therapies, this review documents in- ...
Intervertebral disc degeneration: biological and biomechanical factors
With IVD degeneration, the gradual loss of large PGs, such as aggrecan and versican, from the NP has been reported; however, in the AF, there is an initial ...
In-vitro models of disc degeneration – A review of methods ... - OUCI
Emanuel, K.S., Vergroesen, P.-P.A., Peeters, M., Holewijn, R.M., Kingma, I., Smit, T.H., 2015. Poroelastic behaviour of the degenerating human intervertebral ...
Intervertebral disc degeneration—Current therapeutic options and ...
Numerous animal models were used in preclinical research examining cell therapies for IVD regeneration (452). Mechanical, enzymatic, or surgical methods can be ...
Full article: Original animal model of lumbar disc degeneration
Results: Disc height, water content, and histologic score decreased significantly in the last 3 groups and at all three-time points (P < 0.05). DD progressed ...
In vivo Mouse Intervertebral Disc Degeneration Models and Their ...
While many in vitro models have been developed and used to study IVD pathophysiology and therapeutic strategies, the etiology of IVD ...
A Review of Animal Models of Intervertebral Disc Degeneration ...
Numerous methods of inducing disc degeneration are reported. Broadly these can be considered under the categories of spontaneous degeneration, ...
Preclinical in vivo animal models of intervertebral disc degeneration ...
In these studies, there is great variability in the selection of animals used, method of inducing disc degeneration and measurable experimental ...
ex vivo intervertebral disc cultures: degeneration-induction methods ...
Intervertebral disc-on-a-chip as advanced in vitro model for mechanobiology research and drug testing: a review and perspective. Front Bioeng Biotechnol 9 ...
Deep learning-based high-accuracy quantitation for lumbar ... - Nature
To help doctors and patients evaluate lumbar intervertebral disc degeneration (IVDD) accurately and efficiently, we propose a segmentation ...
Relevance of In Vitro and In Vivo Models for Intervertebral - JBJS
Models available for the study of intervertebral disc degeneration are designed to answer many important questions. In vitro biologic models employ a ...
In vivo experimental intervertebral disc degeneration induced by ...
Recently, biological therapies for early intervention of degenerative disc disease have been introduced and developed; however, a functional ...
Analysis of Intervertebral Disc Degeneration Testing Method
This research was completed in order to develop a viable model of intervertebral disc degeneration in vitro that could be used for future ...
Painful intervertebral disc degeneration and inflammation - Nature
Puncture models, mechanical models, and spontaneous models as the main animal models to study painful disc degeneration are discussed, and the ...
Development and Degeneration of the Intervertebral Disc—Insights ...
The predominantly avascular nature of the IVD contributes to its uniquely harsh microenvironment. Fournier et al. performed a scoping review analyzing ...
Intervertebral disc creep behaviour through viscoelastic models
An in-vitro study was performed on seven human lumbar spine specimens (L4-5), to assess if the classical rheological models and Nutting's power law can model ...
Animal Models of Intervertebral Disc Degeneration | Request PDF
Over the years, various small and large animal disc degeneration models have been created, but the techniques used are inconsistent, and the outcomes are not ...