Inactivation of adenosine receptor 2A suppresses endothelial|to ...

Inactivation of adenosine receptor 2A suppresses endothelial-to ...

We showed that Adora2a-dependent endothelial-to-mesenchymal transition contributed to the development of subretinal fibrosis in mice with laser ...

Inactivation of adenosine receptor 2A suppresses endothelial-to ...

In addition to EndMT, suppressing subretinal fibrosis after inactivation of endothelial ADORA2A is attributed to many other mechanisms. We have ...

Inactivation of adenosine receptor 2A suppresses endothelial-to ...

Using a combination of human and rodent models with genetic and pharmacologic approaches, we provide evidence that ADORA2A in choroidal ECs is ...

Inactivation of adenosine receptor 2A suppresses endothelial-to ...

Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice. Qiuhua Yang, Yongfeng Cai ...

Data -- Inactivation of adenosine receptor 2A suppresses ... - Dryad

The introduction of anti-vascular endothelial growth factor therapy has had a substantial impact on the treatment of choroidal neovascularization (CNV) in ...

Blockade of endothelial adenosine receptor 2 A suppresses ...

Recently, we reported that endothelial adenosine receptor 2 A (ADORA2A), a G protein-coupled receptor (GPCR), plays critical roles in neovascularization disease ...

Contents | Science Translational Medicine 16, 737

Subretinal fibrosis is ameliorated by inhibition of endothelial adenosine receptor 2A in two mouse models. Abstract.

Inactivation of endothelial adenosine A2A receptors protects mice ...

Inactivation of the gene for adenosine A2A receptors (ADORA2A for humans and Adora2a for rodents) protects against brain injury in experimental ...

Inactivation of the Adenosine A2A Receptor Protects Apolipoprotein ...

However, unexpectedly, A2AR deficiency in mice or bone marrow–derived cells dramatically inhibits atherosclerosis. Increased apoptosis of foam ...

Inactivation of Adenosine A2A Receptor Attenuates Basal and ...

Cell Biology. Inactivation of Adenosine A2A Receptor Attenuates Basal and Angiotensin II-induced ROS Production by Nox2 in Endothelial Cells*.

Blockade of endothelial adenosine receptor 2A suppresses ...

Blockade of endothelial adenosine receptor 2A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.

Adenosine receptor 2A-mediated HIF signaling enhances ... - IOVS

One of underlying mechanisms is development of fibrosis in nAMD lesion. Thus, therapeutic strategies for the inhibition of subretinal fibrosis are imperative.

Abstract 310: Adenosine Receptor 2A-mediated Endothelial ...

We have previously shown that inactivation of adenosine 2A receptor (ADORA2A) inhibits the formation of atherosclerosis lesion in mice.

Endothelial adenosine A2a receptor-mediated glycolysis is essential ...

Adenosine/adenosine receptor-mediated signaling has been implicated in the development of various ischemic diseases, including ischemic ...

(PDF) Blockade of endothelial adenosine receptor 2 A suppresses ...

Recently, we reported that endothelial adenosine receptor 2 A (ADORA2A), a G protein-coupled receptor (GPCR), plays critical roles in ...

Endothelial adenosine A2a receptor-mediated glycolysis is essential ...

It is shown that adenosine receptor A2A drives pathological angiogenesis in the oxygen-induced retinopathy mouse model by promoting ...

Blockade of endothelial adenosine receptor 2 A suppresses ... - OUCI

Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.

Regulation of endothelial intracellular adenosine via ... - Nature

Our study showed that ADK inactivation elevates intracellular adenosine and inhibits inflammatory response via decreasing the pro-inflammatory ...

Myeloid Expression of Adenosine A2A Receptor Suppresses T and ...

The current study provides evidence indicating that macrophage A2ARs have great potential as therapeutic targets. It is important to note that Adora2a is ...

Adenosine A2A receptor is a unique angiogenic target of HIF-2α in ...

Finally, endothelial cells in which adenosine A2A receptor was activated exhibited increased cell sprouting resulting in formation of branches ...