Incretin therapies in the management of elderly patients with type 2 ...

Aging is characterized by a progressive increase in the prevalence of type 2 diabetes mellitus (T2DM), which approaches 20% by age 70 years. Older patients ...

New approaches to treating type 2 diabetes mellitus in the elderly

There is strong evidence that use of incretin therapy, in particular, the DPP-4 inhibitors, could offer significant advantages in older persons. Clinical ...

Incretin Therapies in the Management of Elderly Patients with Type ...

Abstract: Aging is characterized by a progressive increase in the prevalence of type 2 diabetes mellitus (T2DM), which approaches 20% by age 70 years. Older ...

Incretin therapies in the management of elderly patients with type 2 ...

"Incretin therapies," comprising the injectable GLP-1 analogs and oral dipeptidyl peptidase-4 (DPP-4) inhibitors, are promising new therapies for use in older ...

Incretin-related therapies therefore have a clear clinical utility in patients such as the elderly, who are at high risk of, or at extra risk ...

Focus on Incretin-Based Therapies for Elderly Patients with Type 2 ...

Neumiller, J.J. ∙ Setter, S.M.. Pharmacologic management of the older patient with type 2 diabetes mellitus. Am J Geriatr Pharmacother. 2009; 7:324-342.

Use of Incretin Therapy in the Treatment of Type 2 Diabetes Mellitus

GLP-1 RA and DPP-4 inhibitors are well-tolerated options that improve glycemic control with a low incidence of hypoglycemia and weight gain. •. This article ...

Incretin Therapies for Patients with Type 2 Diabetes and Chronic ...

Figure 2. Incretin effects on structural kidney damage observed in diabetic kidney disease. ... (b) Treatment with incretin-based therapies can ameliorate the ...

Incretin-Based Therapies in Type 2 Diabetes Mellitus

Exenatide (synthetic exendin-4) is the only GLP-1R agonist approved by regulatory agencies as an adjunct therapy to patients with T2DM not achieving ...

Cognitive protection of incretin‐based therapies in patients with type ...

Cognitive dysfunction is recognized as an complication of type 2 diabetes mellitus. Incretin has emerged as a potential therapeutic agent ...

1007-P: Incretin Therapy with DPP-4-I and GLP1-RA for the Hospital ...

Management of hospitalized older adults (> 65 years) with T2D is challenging and associated with increased risk of hypoglycemia.

Treatment of type 2 diabetes mellitus in the older patient - UpToDate

Once insulin secretion and sensitivity are improved, the dose can be lowered or replaced with metformin or another glucose-lowering agent with ...

Incretin based treatments and mortality in patients with type 2 diabetes

Conclusions Current evidence does not support the suggestion that incretin based treatment increases all cause mortality in patients with type 2 ...

Incretin-Based Therapies in Complex Patients: Practical Implications ...

Older patients with type 2 diabetes—like patients with renal insufficiency an important and populous subgroup—also have issues with therapy selection and dosing ...

Antihyperglycaemic therapy in elderly patients with type 2 diabetes ...

Newer agents based on enhancing incretin activity, including the glucagon-like peptide-1 mimetics exenatide and liraglutide and the oral ...

Incretin-based therapy: a powerful and promising weapon in the ...

Incretin-based treatment modalities, and in particular glucagon-like peptide 1 (GLP-1) receptor agonists, are able to successfully counteract several of the ...

Antihyperglycaemic therapy in elderly patients with type 2 diabetes ...

Newer agents based on enhancing incretin activity, including the glucagon‐like peptide‐1 mimetics exenatide and liraglutide and the oral dipeptidyl ...

Incretin Therapies in the Management of Elderly Patients with Type ...

Incretin Therapies in the Management of Elderly Patients with Type 2 Diabetes Mellitus. Isabelle Bourdel-Marchasson. ,. Anja SCHWEIZER. ,. Sylvie Dejager.

Incorporating Incretin-Based Therapies into Clinical Practice for ...

Data indicate and clinical experience confirms that incretins are well tolerated in appropriate patients and provide sustained glycemic control ...

Treating Patients With Type 2 Diabetes -- Incretin-Based Therapies

How do you choose between the incretin-based therapies, and where do they fit into the treatment algorithm of T2DM? Authors: Frank Svec, MD, PhD.