Induction of Chromosome Instability by Activation of Yes|Associated ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

By analyzing cell lines, genetically modified mice, and HCC tissues, we found that YAP cooperates with FOXM1 to contribute to chromosome ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

YAP Induces its Interaction Partner FOXM1 to Regulate CIN Genes. FOXM1 is a master regulator of cell-cycle control and part of the CIN25/CIN70 signatures.

Induction of Chromosome Instability by Activation of Yes-Associated ...

The Hippo pathway effector YAP induces its interaction partner FOXM1 to drive the expression of genes associated with CIN in HCC cells.

References in Induction of Chromosome Instability by Activation of ...

Many different types of cancer cells have chromosome instability. The hippo pathway leads to phosphorylation of the transcriptional activator yes-associated ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

We analyzed transcriptome data from 242 patients with hepatocellular carcinoma (HCC) to search for gene signatures associated with chromosomal instability (CIN); ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

... The most frequent aberrations encompass gain of 1q, 8q, 17q, or 20q and loss of 4q, 8p, 13q, 16q, or 17p (10,11). These alterations have ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer. Sofia M.E. Weiler, Federico Pinna, Thomas ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer. more hide. Show All Show Less. Author/Creator.

Induction of Chromosome Instability by Activation of Yes-Associated ...

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer · Sofia M.E. Weiler · Federico Pinna · Thomas Wolf ...

YAP-associated chromosomal instability and cholangiocarcinoma in ...

Deregulated Hippo pathway signaling is associated with aberrant activation of the downstream effector yes ... induces CCA in mice. To ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer. Background & Aims Many different types of ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

Article "Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer" Detailed information of the ...

Chromosomal instability-induced senescence potentiates cell non ...

The increase in DNA damage correlated with elevated levels of senescence-associated markers p53 activation (phosphorylation on serine 15 residue ...

Kaposi's Sarcoma-Associated Herpesvirus Induction of ...

Alterations such as chromosome deletions, translocations, inversions, and microsatellite instability often lead to the activation of a proto-oncogene(s) and/or ...

The emerging links between chromosomal instability (CIN ...

Induction of genomic instability and activation of autophagy in artificial human aneuploid cells. ... NF-κB-inducing kinase is a key regulator of ...

The Multifaceted Role of Chromosomal Instability in Cancer and Its ...

Overcoming CIN-Induced Immune Activation. The prevalence of CIN in human cancer indicates that, at some point during tumor evolution, tumor ...

FOXM1 is critical for the fitness recovery of chromosomally unstable ...

Induction of chromosome instability by activation of Yes-associated protein and forkhead box M1 in liver cancer. Gastroenterology 2017;152 ...

Induction of Chromosome Instability by Activation of Yes-Associated ...

Read and download Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer by Sofia M.E. Weiler, ...

Chronic chromosome instability induced by Plk1 results in immune ...

We overexpress Polo-like kinase 1 (Plk1) in a Her2 + breast cancer model. These high-CIN tumors activate a senescence-associated secretory phenotype (SASP).

Chromosomal instability induced in cancer can enhance ... - eLife

Additionally, macrophages often polarize toward tumor-associated macrophage (TAM) phenotypes that tend to correlate with poor clinical prognoses ...