• Interplay Between NLRP3 Inflammasome and Autophagy🔍
• Inflammasome and Autophagy Regulation🔍
• Inflammasome and autophagy regulation🔍
• Regulation of inflammasomes by autophagy🔍
• Targeting autophagy regulation in NLRP3 inflammasome|mediated ...🔍
• The Role of the Effects of Autophagy on NLRP3 Inflammasome in ...🔍
• Crosstalk between Autophagy and Inflammasomes🔍
• Crosstalks between inflammasome and autophagy in cancer🔍

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers

In the last decade numerous studies have further indicated that autophagy can regulate inflammasome activation, including the NLRP3 inflammasome activation, ...

Inflammasome and Autophagy Regulation: A Two-way Street - PMC

Autophagic removal of intracellular DAMPs, inflammasome components or cytokines can reduce inflammasome activation. Similarly, inflammasomes can regulate the ...

Inflammasome and autophagy regulation - a two-way street - PubMed

Inflammation plays a significant role in protecting hosts against pathogens. Inflammation induced by non-infectious, endogenous agents can be detrimental, ...

Regulation of inflammasomes by autophagy

Recent studies have shown that autophagy, an intracellular degradation system associated with maintenance of cellular homeostasis, plays a key role in ...

Regulation of inflammasomes by autophagy

Here we review recent findings regarding the involvement of autophagy in the regulation of inflammasome activation and development of inflammatory disorders. (J ...

Targeting autophagy regulation in NLRP3 inflammasome-mediated ...

We highlight the therapeutic potential of autophagy activators in COVID-19 by inhibiting the NLRP3 inflammasome, thereby avoiding the cytokine storm.

The Role of the Effects of Autophagy on NLRP3 Inflammasome in ...

In recent years, autophagy has been reported to play a vital role by regulating the NLRP3 inflammasome in inflammatory nervous system diseases.

Crosstalk between Autophagy and Inflammasomes - ScienceDirect

Defects in the autophagy process are associated with a variety of human diseases, including inflammatory and metabolic diseases. The inflammasomes are emerging ...

Crosstalks between inflammasome and autophagy in cancer

Both inflammasomes and autophagy have important roles in the intracellular homeostasis, inflammation, and pathology; the dysregulation of ...

Regulation of the NLRP3 inflammasome by autophagy and mitophagy

The NLRP3 inflammasome is a multiprotein complex that upon activation by the innate immune system drives a broad inflammatory response.

Regulation of Inflammasome by Autophagy - SpringerLink

Autophagy is a fundamental and conserved degradation system in events of nutrient starvation or metabolic stress. It regulates inflammasome ...

Interaction among inflammasome, autophagy and non-coding RNAs

Autophagy and inflammasomes are shown to interact in various situations including infectious disease, cancer, diabetes and neurodegeneration.

Autophagy Regulation on Pyroptosis: Mechanism and Medical ...

In another study, scientists found that the mitophagy/autophagy system acted as a suppressor of NLRP3 inflammasome activation through scavenging ...

Regulation Where Autophagy Intersects the Inflammasome

Significance: The autophagy and inflammasome pathways are ancient innate immune mechanisms for controlling invading pathogens that are linked by mutual ...

Inflammasome and Autophagy Regulation: A Two-way Street

Autophagy has now been identified as a main regulator of inflammasomes, allowing for a two-way mutual regulation of inflammation that may hold the key for ...

Full article: Autophagy balances inflammation in innate immunity

However, autophagy does not exclusively play a negative role in the regulation of inflammasomes. Despite its general suppressive effects on the inflammasome ...

Inflammaging: disturbed interplay between autophagy ... - Aging-US

The decline in autophagy with aging impairs cellular housekeeping and exposes cells to the risk of inflammasome activation. There is now convincing experimental ...

An update on the regulatory mechanisms of NLRP3 inflammasome ...

Ubiquitination of NLRP3 by several E3 ligases is generally thought to abrogate inflammasome activation. Autophagic degradation of the NLRP3 ...

The Roles of Autophagy and the Inflammasome during ... - MDPI

The regulation of the inflammasome with respect to skin inflammation is complex and is still not completely understood. Autophagy, an intracellular degradation ...

Autophagy proteins regulate innate immune responses by inhibiting ...

Release of mtDNA into the cytosol depended on the NALP3 inflammasome and mitochondrial reactive oxygen species (ROS). Cytosolic mtDNA ...