Insights of the pathophysiology of neurodegenerative diseases and ...

Abstract. A neurodegenerative disease (ND) is defined as an irreversible disorder in most cases, leading to progressive loss of neurons and ...

Insights of the pathophysiology of neurodegenerative diseases and the role of phytochemical compounds in its management

an interplay among axonal transport failure, oxidative stress, and ...

Neurodegenerative diseases (NDs) are heterogeneous neurological disorders characterized by a progressive loss of selected neuronal populations.

Insights of the pathophysiology of neurodegenerative diseases and ...

A neurodegenerative disease is defined as an irreversible disorder in most cases, leading to progressive loss of neurons and intellectual abilities, and the ...

Neurodegenerative diseases: new concepts of pathogenesis and ...

Abstract Neurodegenerative diseases as diverse as Alzheimer's, Parkinson's, and Creutzfeldt-Jakob disease share a common pathogenetic mechanism involving ...

Insights into the Pathogenesis of Neurodegenerative Diseases - MDPI

It appears that oxidative damage induced by free radicals and mitochondrial dysfunction play a major role in both processes.

Neurodegeneration : Insight - Nature

The prevalence of neurodegenerative disorders such as Alzheimer s disease and Parkinson s disease is increasing, but effective treatments are lacking.

New insight on microglia activation in neurodegenerative diseases ...

The pathogenesis of MS is related to an impaired immune response (Dalakas, 2006). The impaired immune response leads to inflammatory cells invading the brain ...

Neurodegenerative disorders report | CAS Insights

Polyglutamine diseases: emerging concepts in pathogenesis and therapy. Hum. Mol. Genet. 2007, 16, Spec No. 2, R115–123. 32. Costa, M. D.; Maciel ...

New Insights into Molecular Mechanisms Underlying ... - IMR Press

Investigations of the potential pathogenesis of neurodegenerative diseases will become the basis of preventing the occurrence and development of ...

Insights on aspects of apoptosis in neurodegenerative disorders

Nerve cell death is the central aspect of human neurodegenerative disorders. Neuronal death in results leads to the onset of various human ...

The Mechanisms Behind Neurodegenerative Diseases

The Mechanisms Behind Neurodegenerative Diseases: New Insights on Alzheimer's, Parkinson's, and ALS · Contents · Neurodegenerative conditions pose their own ...

Implications of glial metabolic dysregulation in the pathophysiology ...

Altered brain energy metabolism and chronic neuroinflammation are common features of several neurodegenerative diseases. Microglia and astrocytes are the major ...

Mechanistic insights into the pathogenesis of neurodegenerative ...

Neurodegeneration is a prevalent and one of the emerging reasons for morbidity, mortality, and cognitive impairment in aging.

Role of the Exposome in Neurodegenerative Disease: Recent ...

Combining large genome-wide association study datasets or genetic data with exposure information provides additional insight into the role an ...

Comprehensive Insights into Pathophysiology of Alzheimer's Disease

Alzheimer's disease [AD] is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and functional impairment.

Early synaptic pathophysiology in neurodegeneration - Cell Press

Investigations of synaptic transmission and plasticity in mouse models of Huntington's disease (HD) demonstrate neuronal dysfunction long ...

Fatty Acids: An Insight into the Pathogenesis of Neurodegenerative ...

Considering the complexity of the response to PA and the intrinsic differences of the brain, in this review, we provide an overview of the molecular and ...

Alzheimer's disease: Insights and new prospects in disease ...

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases that affect millions of people worldwide, with both prevalence and ...

New pathogenic insights from large animal models of ...

Here we highlight the unique nature of large animals to model neurodegenerative diseases as well as the limitations and challenges in establishing large animal ...