Insights on aspects of apoptosis in neurodegenerative disorders

In this paper, a summary of the engrossment of oxidative stress, neuronal apoptosis, and mitochondrial dysfunction in neurodegenerative disorders has been ...

In this paper, a summary of the engrossment of oxidative stress, neuronal apoptosis, and mitochondrial dysfunction in neurodegenerative ...

Apoptosis in neurodegenerative disorders - PubMed

The identification of specific genetic and environmental factors responsible for these diseases has bolstered evidence for a shared pathway of neuronal death-- ...

Insights on aspects of apoptosis in neurodegenerative disorders

Neuronal death in results leads to the onset of various human neurological disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease, ...

Insights on aspects of apoptosis in neurodegenerative disorders

A summary of the engrossment of oxidative stress, neuronal apoptosis, and mitochondrial dysfunction in neurodegenerative disorders has been discussed.

Insights into the Pathogenesis of Neurodegenerative Diseases - NCBI

It is likely that by the time of clinical diagnosis, the pathogenetic cascades are full-blown and significant numbers of neurons have already ...

Apoptosis in neurodegenerative disorders - SpringerLink

Numbers of nigral toxins such as MPTP, complex I inhibitors, and mitochondrial respiratory inhibitors have been reported to induced apoptotic cell death. These ...

Insights on multiple pathways of programmed cell death regulated ...

Currently, nanoparticles (NPs) are extensively applied in the diagnosis and treatment of neurodegenerative diseases (NDs). With the rapid ...

Apoptosis and its therapeutic implications in neurodegenerative ...

Neurodegenerative disorders are characterized by progressive loss of particular populations of neurons. Apoptosis has been implicated in the ...

6. Apoptosis in Neurodegenerative Disorders - J-Stage

23) Nasir J, et al. Huntington disease: new insights into the relationship between CAG expansion and disease. Hum Mole Genet 5 Spec No: 143 1, 1996.

Apoptosis in Neurodegenerative Diseases - ScienceDirect.com

These considerations raise the possibility that cell death with pure apoptotic features may not occur in human brains afflicted by neurodegenerative diseases.

Molecular mechanisms of cell death in neurological diseases - Nature

Abnormalities in PCD signalling cascades, such as apoptosis, necroptosis, pyroptosis, ferroptosis, and cell death associated with autophagy as ...

Apoptosis as a general cell death pathway in neurodegenerative ...

The course of apoptotic death is characterized by a massive morphological change, including cell shrinkage, nuclear (chromosome) condensation and DNA ...

Apoptosis and its therapeutic implications in neurodegenerative ...

Apoptosis has been implicated in the pathogenesis of neurodegenerative diseases, including Parkinson disease, Alzheimer disease, Huntington disease, and ...

Molecular Insights into Mechanisms of the Cell Death Program:Role ...

A better understanding of the molecular underpinnings of neuronal apoptosis will lead to novel preventive and therapeutic approaches to the neurodegenerative ...

Hallmarks of neurodegenerative diseases - Cell Press

Mechanistic insights from genetics: Gain of toxic function versus loss of function. The identification of causal mutations for. (rare) inherited ...

Mechanisms of Neurodegenerative Disorders: Part 2: Control of Cell ...

Apoptosis occurs in many pathological situations in the brain, including ischemia, Huntington disease, and AD. In the ischemic brain, apoptotic ...

Neuronal cell death mechanisms in Alzheimer's disease: An insight

Aberrant activation of this pathway results in cell death by various mechanisms including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy- ...

Neurodegenerative disorders report | CAS Insights

In Human Caspases and Neuronal Apoptosis in. Neurodegenerative Diseases, Gupta, A., Ed. Academic Press 2022, 1–67. 6. Suescun, J.; Chandra, S.; Schiess, M. C. ...

Regulated cell death: discovery, features and implications for ...

More and more evidence has confirmed that in human diseases, deregulated apoptosis is implicated in the pathological loss or accumulation of ...