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Integrating DNA Methylation and Gene Expression Data in ...


Integrating DNA methylation and gene expression data in a single ...

We developed the iNETgrate package (https://bioconductor.org/packages/iNETgrate/) that efficiently integrates transcriptome and DNA methylation data in a ...

Integrating DNA Methylation and Gene Expression Data in ... - NCBI

As DNA methylation often affects gene expression, those 89 genes may be at least partially under epigenetic control and worthy of further ...

Integration of gene expression and DNA methylation data across ...

We present INTEND (IntegratioN of Transcriptomic and EpigeNomic Data), a novel algorithm for integrating gene expression and DNA methylation datasets covering ...

Integrative analysis of DNA methylation and gene expression ...

DNA methylation plays important roles in various biological processes, including the regulation of gene expression, genomic imprinting, cell ...

Integration of gene expression and DNA methylation identifies ...

Further, by integrating gene expression with DNA methylation using Functional Epigenetic Modules algorithms, we identified 9 and 6 modules in relation to PM2.5 ...

Integration of Gene Expression and DNA Methylation Data ... - bioRxiv

We present INTEND (IntegratioN of Transcriptomic and EpigeNomic Data), a novel algorithm for integrating gene expression and DNA methylation datasets covering ...

DNA methylation and gene expression integration in cardiovascular ...

Our aim was to integrate DNA methylation and gene expression data in an effort to identify biomarkers related to cardiovascular disease risk in a community- ...

Integrated Analysis of DNA Methylation and Gene Expression ...

We identified 170 genes (100 hypomethylated and upregulated genes and 70 hypermethylated and downregulated genes) regulated by DNA methylation in OA.

Large-scale integration of DNA methylation and gene expression ...

Despite known limitations in predicting the function of a particular CpG site, most EWAS maintain the broad assumption that altered DNAm results in a ...

Identification of DNA methylation-regulated differentially expressed ...

To identify novel DNA methylation-regulated differentially expressed genes (MeDEGs) in RA by integrated analysis of DNA methylation and ...

Identification of key genes by integrating DNA methylation and next ...

Aberrant DNA methylation leads to abnormal gene expression, making it a significant regulator in the progression of cancer and leading to the requirement ...

Integrating DNA methylation and gene expression data in a single ...

However, designing such a model is challenging because different omics are measured at different levels. We developed the iNETgrate package (https:// ...

Integrated DNA Methylation and Gene Expression Analysis ...

This study confirmed the relationship between DNA methylation and gene expression and emphasized the important role of S100A8 and S100A9 in the pathogenesis of ...

MethHC: a database of DNA methylation and gene expression in ...

To obtain human DNA methylation and gene expressions, we integrated the heterogeneous data from TCGA. First, DNA methylation data are specific to the Illumina ...

Integrated Analysis of DNA Methylation and Gene Expression in ...

In this study, we used whole-genome bisulfite sequencing and RNA sequencing to produce a global map of DNA methylation and gene expression changes in placentas.

A deep learning regression model for multi-omics integration

The features extracted from the integrated DNA methylation and copy number variation data form the input to the regression model. The plot for true gene ...

Integration of Gene Expression and DNA Methylation Data Across ...

DNA methylation in mammals occurs almost exclusively in the 5' position of a Cytosine followed by a Guanine, commonly termed a CpG site. CpG ...

(PDF) DNA methylation and gene expression integration in ...

Our aim was to integrate DNA methylation and gene expression data in an effort to identify biomarkers related to cardiovascular disease risk in a community- ...

Integrating DNA methylation and gene expression data in a single ...

(d) We construct an integrative network, in which nodes represent genes and edges model the association between individual gene pairs based on both expression ...

Integrated DNA methylation and gene expression profiling across ...

To functionally validate these associations, we generated and analyzed corresponding transcriptome data to prioritize 130 genes within 10 kb of ...