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Integrating DNA methylation and gene expression data in a single ...


Integrating DNA methylation and gene expression data in a single ...

We developed the iNETgrate package (https://bioconductor.org/packages/iNETgrate/) that efficiently integrates transcriptome and DNA methylation data in a ...

Integrating DNA Methylation and Gene Expression Data in ... - NCBI

Integration of methylation data with gene expression data from the same samples was done to get a first glimpse at the role of epigenetics in ...

Integration of gene expression and DNA methylation data across ...

The regulation of gene expression allows cells to increase or decrease the production of proteins or RNA. Such adjustments enable a response to ...

Integrating DNA methylation and gene expression data in a single ...

(d) We construct an integrative network, in which nodes represent genes and edges model the association between individual gene pairs based on both expression ...

Integrating DNA methylation and gene expression data in a single ...

However, designing such a model is challenging because different omics are measured at different levels. We developed the iNETgrate package (https:// ...

Integration of Gene Expression and DNA Methylation Data ... - bioRxiv

Here, we present INTEND (IntegratioN of Transcriptomic and EpigeNomic Data), a novel algorithm for integrating gene expression and DNA ...

Integrative analysis of DNA methylation and gene expression ...

In the distant regulation of gene expression, the methylation of hypermethylated genes was more likely to be negatively correlated with gene ...

Integrated Analysis of DNA Methylation and Gene Expression ...

Because DNA methylation analysis can provide valuable insights into gene regulation and identify potential biomarkers, genome-wide DNA methylation using methyl- ...

Integration of gene expression and DNA methylation identifies ...

By integrating gene expression and DNA methylation into a protein interaction network we found 9 significant functional epigenetically deregulated modules ...

Integrating DNA methylation and gene expression data in a single ...

AbstractAnalyzing different omics data types independently is often too restrictive to allow for detection of subtle, but consistent, variations that are ...

DNA methylation and gene expression integration in cardiovascular ...

Our aim was to integrate DNA methylation and gene expression data in an effort to identify biomarkers related to cardiovascular disease risk in a community- ...

scBPGRN: Integrating single-cell multi-omics data to construct gene ...

We propose an algorithm to search for regulatory factors associated with target genes. In this process, we use the BP neural network to link the gene expression ...

Integration of gene expression and DNA methylation data across ...

Integrating multiple datasets of different omics remains a challenge, with only a few available algorithms developed to solve it. Here, we ...

Integrated Analysis of DNA Methylation and Gene Expression in ...

The DNA methylation level in the gene promoter was negatively correlated with gene expression. We identified a set of differentially methylated ...

Large-scale integration of DNA methylation and gene expression ...

Despite known limitations in predicting the function of a particular CpG site, most EWAS maintain the broad assumption that altered DNAm results in a ...

Integration of gene expression and DNA methylation data across ...

Integrating multiple datasets of different omics remains a challenge, with only a few available algorithms developed to solve it. Here, we present INTEND ( ...

sion and DNA methylation data in a gene network - Bioconductor

The iNETgrate package is specifically developed to fuse (i.e., effectively integrate) DNA methylation data with gene expression data in a single ...

MethHC: a database of DNA methylation and gene expression in ...

To obtain human DNA methylation and gene expressions, we integrated the heterogeneous data from TCGA. First, DNA methylation data are specific to the Illumina ...

Multiple network algorithm for epigenetic modules via the integration ...

Available methods integrate the DNA methylation and gene expression data into a network by specifying the anti-correlation between them. However ...

Integrative analysis of gene expression, DNA methylation ... - PNAS

We integrate comeasured gene expression and DNA methylation (DNAme) in 265 human skeletal muscle biopsies from the FUSION study with >7 million genetic ...