Integration of Gene Expression and DNA Methylation Data ...

Integration of gene expression and DNA methylation data across ...

We present INTEND (IntegratioN of Transcriptomic and EpigeNomic Data), a novel algorithm for integrating gene expression and DNA methylation datasets covering ...

Integration of gene expression and DNA methylation data ... - PubMed

Integrative analysis of multi-omic datasets has proven to be extremely valuable in cancer research and precision medicine.

Integrating DNA methylation and gene expression data in a single ...

We developed the iNETgrate package (https://bioconductor.org/packages/iNETgrate/) that efficiently integrates transcriptome and DNA methylation data in a ...

Integrative analysis of DNA methylation and gene expression ...

DNA methylation plays important roles in various biological processes, including the regulation of gene expression, genomic imprinting, cell ...

Integration of gene expression and DNA methylation identifies ...

By integrating gene expression and DNA methylation into a protein interaction network we found 9 significant functional epigenetically deregulated modules ...

Multi‐omic integration of DNA methylation and gene expression ...

Multi‐omic integration of DNA methylation and gene expression data reveals molecular vulnerabilities in glioblastoma

Integrative analysis of DNA methylation and gene expression ...

Here, our study systematically analyzed the genome-wide DNA methylation status, combined with transcriptome data, and finally identified a set ...

Integrated analysis of genome-wide gene expression and DNA ...

Integrated analysis revealed that DNA methylation was negatively correlated to gene expression in most genomic regions, such as exon, 3'UTR, 5'UTR, and promoter ...

Multi-view Clustering for the Integration Analysis of Gene Expression ...

Abstract: The accumulated gene expression and DNA methylation data provide a great opportunity to exploit the mechanisms of biological systems.

Large-scale integration of DNA methylation and gene expression ...

Despite known limitations in predicting the function of a particular CpG site, most EWAS maintain the broad assumption that altered DNAm results in a ...

A deep learning regression model for multi-omics integration

The features extracted from the integrated DNA methylation and copy number variation data form the input to the regression model. The plot for true gene ...

DNA methylation and gene expression integration in cardiovascular ...

was to integrate DNA methylation and gene expression data in an effort to identify biomarkers related to cardiovascular disease risk in a ...

Integrative analysis of DNA methylation and gene expression data ...

DNA methylation is one of the main epigenetic mechanisms and associated with the gene expression and disease initiation of PD. We aimed to construct a ...

MethHC: a database of DNA methylation and gene expression in ...

To obtain human DNA methylation and gene expressions, we integrated the heterogeneous data from TCGA. First, DNA methylation data are specific to the ...

Multi-View Clustering for Integration of Gene Expression and ...

Abstract: The accumulated DNA methylation and gene expression provide a great opportunity to exploit the epigenetic patterns of genes, ...

Integrative analysis of gene expression, DNA methylation ... - PNAS

We integrate comeasured gene expression and DNA methylation (DNAme) in 265 human skeletal muscle biopsies from the FUSION study with >7 million genetic ...

Integrated Analysis of DNA Methylation and Gene Expression in ...

The DNA methylation level in the gene promoter was negatively correlated with gene expression. We identified a set of differentially methylated ...

Identification of key genes by integrating DNA methylation and next ...

Aberrant DNA methylation leads to abnormal gene expression, making it a significant regulator in the progression of cancer and leading to the requirement ...

Integration of gene expression and DNA methylation data across ...

We also demonstrate INTEND's ability to uncover connections between DNA methylation and the regulation of gene expression in the joint analysis ...

Integration of public DNA methylation and expression networks via ...

Gene co-expression networks can be used to infer functional relationships between genes, but they do not work well for all genes. We ...