Integrative omics|analysis of lipid metabolism regulation by ...

Integrative omics-analysis of lipid metabolism regulation by ...

Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome ...

Integrative omics-analysis of lipid metabolism regulation ... - Frontiers

Here we study the involvement of Atlantic cod Ppar a and b subtypes in systemic regulation of lipid metabolism using two model agonists after in vivo exposure.

Integrative omics-analysis of lipid metabolism regulation by ... - NCBI

By using in vitro and in vivo approaches, we have shown that WY-14,643 and GW501516 activate Atlantic cod Ppars, affect genes in lipid ...

(PDF) Integrative omics-analysis of lipid metabolism regulation by ...

PDF | Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated.

Integrative analyses of TEDDY Omics data reveal lipid metabolism ...

Another key component of our model is the peroxisome proliferator-activated receptor-α (PPARα), which displayed lower expression in cases (Fig.

An integrative multiomic network model links lipid metabolism to ...

By integrating gene expression, genotype, metabolomic, and clinical data, we identify a glucose and lipid determining (GLD) regulatory network ...

Integrative metabolomic and transcriptomic analysis reveals ...

Genes related to glucose uptake, glycolysis, glycogen synthesis, fatty acid synthesis (PFKFB1, PFKFB4, MPI, TPI1, GYS1, SLC2A4, FASN, IRS1, ULK1) are more ...

Multi-omics integrative analysis to access role of coiled-coil domain ...

Lipid metabolism is an intricate physiological process essential for energy homeostasis [1]. It is precisely regulated in healthy humans [2] and other animals [ ...

Abstract 40: Integrative Genomics Analysis Reveals Novel ...

Our results shed lights on the complex mechanisms underlying lipid metabolism and highlight potential novel targets for lipid regulation.

Integrative analysis of miRNAs and mRNAs revealed regulation of ...

Lipid metabolism in bovine mammary epithelial cells has been the primary focus of the research of milk fat percentage of dairy cattle.

Mapping Condition-Dependent Regulation of Lipid Metabolism in ...

To query this network, we developed integrative methods for correlation of multi-omics datasets that elucidate global regulatory signatures. Our data highlight ...

Integrated meta-omics reveals the regulatory landscape involved in ...

The findings enhanced our understanding of the cellular biology of lipid metabolism and opened new avenues to improve animal production and ...

Integrative analysis of the characteristic of lipid metabolism-related ...

Dysregulation of lipid metabolism is implicated in the progression of hepatocellular carcinoma (HCC). We therefore investigated the molecular characteristics of ...

Integrative omics-analysis of lipid metabolism regulation by ... - X-MOL

Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod.

Integrative Metabolomics and Transcriptomics Identify Lipid ... - IOVS

Earlier, we showed a significant association of genes involved in cholesterol metabolism, and immune regulation in retinopathy of prematurity (ROP) pathogenesis ...

Integrated Transcriptomic and Lipidomics Analysis

Combined transcriptomics and lipidomics analysis can provide valuable insights into the complex relationship between gene expression and lipid metabolism，which ...

An integrative systems genetic analysis of mammalian lipid ...

... lipid regulatory networks in 107 genetically distinct mouse strains to reveal key insights into the control and network structure of mammalian lipid metabolism ...

Integrative analysis of bulk and single-cell transcriptomic data ...

Genes associated with lipid metabolism in liver cells were identified, and a machine-learning model was developed using the bulk transcriptomic ...

Integrative Analysis Reveals the Diverse Effects of 3D Stiffness upon ...

For example, alterations in ECM stiffness affect glucose, lipid, and amino acid metabolism, thereby altering cell phenotype and regulation of ...

Gene networks and pathways for plasma lipid traits via multitissue ...

... metabolic pathways in HDL regulation is recapitulated by our analysis. ... An integrative systems genetic analysis of mammalian lipid metabolism. Nature ...