Interaction between the epidermal growth factor receptor

Biochemistry, Epidermal Growth Factor Receptor - StatPearls - NCBI

... EGF ligands to the extracellular domain promotes receptor ... interaction with kinase-active receptors such as EGFR, ErbB2, and ErbB4.

Interaction between the epidermal growth factor receptor ... - PubMed

Ligand-activated epidermal growth factor (EGF) receptors are coupled to the phosphatidylinositol (PtdIns) pathway to stimulate formation of ...

Interaction between the epidermal growth factor receptor (EGFR ...

Interaction between the epidermal growth factor receptor (EGFR) and the vascular endothelial growth factor (VEGF) pathways: a rational approach for multi ...

Interaction between the epidermal growth factor receptor and ...

Ligand-activated epidermal growth factor (EGF) receptors are coupled to the phosphatidylinositol (PtdIns) pathway to stimulate formation of two second ...

The Epidermal Growth Factor Receptor Pathway: A Model for ...

Although Src functions independently, it also cooperates with other receptor tyrosine kinases signaling. The interaction between EGFR and Src is ...

ATP-stimulated interaction between epidermal growth factor ... - Nature

The receptor for epidermal growth factor (EGF) has been identified as a transmembrane glycoprotein that has tyrosine-specific kinase ...

Physical Interaction between Epidermal Growth Factor Receptor and ...

Our findings demonstrate the existence of a novel cellular pathway in mammalian cells that involves physical interactions between EGFR and DNA-PK or Ku70/80

Multiple-state reactions between the epidermal growth factor ... - PNAS

The epidermal growth factor receptor (EGFR) is a transmembrane receptor protein embedded in the plasma membrane of many types of cells and is responsible for ...

Heterodimerization and functional interaction between EGF receptor ...

This review summarizes current work on heterodimerization and attempts to predict the consequences for downstream signaling.

Crystal Structure of the Complex of Human Epidermal Growth Factor ...

Epidermal growth factor (EGF) regulates cell proliferation and differentiation by binding to the EGF receptor (EGFR) extracellular region, ...

Epidermal growth factor receptor signaling intensity determines ...

By using mAb 806, which recognizes an EGFR-activation state and preferentially immunoprecipitates ΔEGFR, we show that ΔEGFR did not interact with Cbls, SETA, or ...

Coordinated Traffic of Grb2 and Ras during Epidermal Growth ...

To study trafficking and interactions of molecules involved in EGF-induced Ras activation, YFP and CFP fusion proteins of EGFR, Grb2, Shc, and Ras were ...

Epidermal growth factor receptor (EGFR) and EGFR mutations ...

This tyrosine kinase phosphorylates a number of intracellular substrates that activates pathways leading to cell growth, DNA synthesis and the expression of ...

Epidermal Growth Factor Receptor: Key to Selective Intracellular ...

Interaction of a ligand with the EGFR domains I and III releases the arm facilitating contact with the neighboring receptor [7]. Inactive EGFR ...

Comparing the Epidermal Growth Factor Interaction - ProQuest

The interaction of the epidermal growth factor (EGF) with its receptor (EGFR) is known to be complex, and the common over-expression of EGF receptor family ...

EGFR - Epidermal growth factor receptor - Homo sapiens (Human)

Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin (PubMed:11483589). Positively regulates cell migration via interaction ...

Structural Analysis of Interactions between Epidermal Growth Factor ...

People's lives and health are gravely threatened by non-small-cell lung cancer (NSCLC). Mutations in epidermal growth factor receptor (EGFR) ...

Expression and Function of the Epidermal Growth Factor Receptor ...

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of membrane-associated intrinsic tyrosine kinase receptors, the ErbB ...

Stoichiometric Interaction of the Epidermal Growth Factor Receptor ...

Hence, we analyzed the stoichiometry of the EGF receptor interaction with AP-2 using a new antibody that efficiently immunoprecipitates native AP-2. EGF ...

Interaction of epidermal growth factor with its receptor.

23 Citations · Growth factor receptors: structure, mechanism, and drug discovery. · Structure-function studies of ligand-induced epidermal growth factor receptor ...