Interactions with DNA
DNA interactions: understanding what your DNA is up to
DNA doesn't work alone, interacting with other nucleic acids – DNA and RNA – as well as different types of proteins. These interactions influence various ...
Interactions with DNA - an overview | ScienceDirect Topics
The interplay between protein and DNA are ubiquitous in nature and governs several cellular processes (replication, transcription, translation, chromosomal ...
DNA–DNA interactions | The Aksimentiev Group
We combine fluorescence resonance energy transfer (FRET) measurements, precipitation assays, and molecular dynamics simulations to characterize the effect of ...
Protein–DNA/RNA Interactions: An Overview of Investigation ... - NCBI
The present review proposes an overview of the approaches most commonly employed in proteomics applications for the identification of nucleic acid-binding ...
Interactions That Hold DNA Together - News-Medical
There are several interactions present within a strand and between two strands that stabilize the DNA.
Interactions with DNA - an overview | ScienceDirect Topics
The hyperchromic effect is the outstanding increase in absorbance of DNA upon denaturation. The two strands of DNA are held together mainly by the stacking ...
DNA–protein interaction studies: a historical and comparative analysis
This review intends to provide a historical context and compile the methods that describe DNA–protein interactions according to the purpose of each approach.
Methods for Detecting Protein-DNA Interactions - US
The ChIP assay method allows analysis of DNA–protein interactions in living cells by treating the cells with formaldehyde or other crosslinking reagents in ...
Interaction of DNA with clusters of amino acids in proteins - PMC
Graph spectral algorithm has been used to detect side chain clusters comprising Arg, Lys, Asn, Gln and aromatic residues from proteins interacting with DNA. We ...
Spatiotemporal and global profiling of DNA–protein interactions ...
Precise dissection of DNA–protein interactions is essential for elucidating the recognition basis, dynamics and gene regulation mechanism.
Understanding DNA interactions in crowded environments with a ...
We use a coarse-grained model of DNA to study the kinetics and thermodynamics of DNA duplex and hairpin formation in crowded environments.
Overview of Protein-Nucleic Acid Interactions - CA
Proteins interact with DNA and RNA through similar physical forces, which include electrostatic interactions (salt bridges), dipolar interactions (hydrogen ...
Determining the specificity of protein–DNA interactions - Nature
Traditional methods for determining the specificity of DNA-binding proteins are slow and laborious, but several new high-throughput methods can provide ...
Introduction to Protein-DNA Interactions: Structure, Thermodynamics ...
Describes what we know about protein–DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics.
DNA-binding protein - Wikipedia
DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. ... Sequence- ...
DNA Interactions with Proteins - News-Medical
During the process of complex formation, hydrogen bonds between the polar amino acids and the atoms of the DNA molecule augment the affinity of ...
DNA-Protein Interaction Analysis - Illumina
Analyzing DNA-protein interactions with sequencing. By combining chromatin immunoprecipitation (ChIP) and massively parallel sequencing, ChIP-Seq accurately ...
Protein:DNA Interactions - Promega Corporation
Chromatin immunoprecipitation (ChIP) is a method used to determine whether DNA-binding proteins, such as transcription factors, associate with a specific ...
Metal complex interactions with DNA - Dalton Transactions (RSC ...
Increasing numbers of DNA structures are being revealed using biophysical, spectroscopic and genomic methods. The diversity of transition metal complexes is ...
Chromatin Immunoprecipitation Reveals DNA-Protein Interactions
These initial experiments established the feasibility of protein-DNA crosslinks in intact cells combined with immunoprecipitation.