Interplay Between NLRP3 Inflammasome and Autophagy

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers

This review will focus on the current available information about this mutual regulation that exist between NLRP3 inflammasome and autophagy.

Interplay Between NLRP3 Inflammasome and Autophagy - PubMed

The NLRP3 inflammasome is cytosolic multi-protein complex that induces inflammation and pyroptotic cell death in response to both pathogen ...

Interplay Between NLRP3 Inflammasome and Autophagy - PMC

Autophagy has a protective role in some inflammatory diseases associated with NLRP3 inflammasome, including gouty arthritis, familial Mediterranean fever (FMF) ...

The Role of the Interplay Between Autophagy and NLRP3 ... - Frontiers

There are two mechanisms of the effects of autophagy on NLRP3 inflammasome: one is that autophagy inhibits NLRP3 inflammasome by scavenging ROS ...

Interaction between autophagy and the NLRP3 inflammasome

Atg5 acetylation inhibits autophagy, and the NLRP3 inflammasome is overactivated in Atg5-acetylated cells. In contrast, autophagy is activated ...

The Complex Interplay between Autophagy and NLRP3 ... - MDPI

In this review, the interplay between autophagy and the NLRP3 inflammasome and the mechanisms in renal diseases are explored to provide ideas for relevant ...

The role of vitamin D3 in modulating the interplay between NLRP3 ...

The current study suggests that CAL was capable of ameliorating NASH via inhibiting NLRP3 inflammasome activation in an autophagy-dependent manner.

An update on the regulatory mechanisms of NLRP3 inflammasome ...

Autophagy and inflammasome interplay. DNA Cell Biol ... NLRP3 inflammasome activation through blocking interaction between NLRP3 and NEK7.

Interplay Between NLRP3 Inflammasome and Autophagy

Inflammasome signaling pathways can regulate autophagic process necessary for balance between required host defense inflammatory response and prevention of ...

The Interplay between Autophagy and NLRP3 Inflammasome in ...

Studies have shown that autophagy and the NLRP3 inflammasome play an important role in the process of I/R injury, but the relevant mechanisms have not been ...

Interaction between autophagy and the NLRP3 inflammasome in ...

Autophagy degrades phagocytosed damaged organelles, misfolded proteins, and various pathogens through lysosomes as an essential way to maintain cellular ...

The Interplay between Autophagy and NLRP3 Inflammasome in ...

Studies have shown that autophagy and the NLRP3 inflammasome play an important role in the process of I/R injury, but the relevant mechanisms ...

Relationship between autophagy and NLRP3 inflammasome during ...

This study evaluated the immunoexpression of autophagy and NLRP3-inflammasome markers, in rat articular cartilage with estrogen deficiency and DM.

Inflammasome and Autophagy Regulation: A Two-way Street

Another hypothesis involves the interaction between thioredoxin-interacting protein (TXNIP) and NLRP3, which has been shown to be crucial ...

Inflammaging: disturbed interplay between autophagy ... - Aging-US

In general, the expression levels of NLRP3 receptor as well as the precursors of IL-1β and IL-18 remain low and activation of NLRP3 inflammasomes requires a ...

Interaction among inflammasome, autophagy and non-coding RNAs

A portion of ASC-containing inflammasomes are found to be redirected towards autophagosomes and autophagolysosomes upon NLRP3 or AIM2 activation ...

Small molecule-driven NLRP3 inflammation inhibition via interplay ...

Many regulatory mechanisms have been identified that attenuate NLRP3 inflammasome signaling at multiple steps. Among them, the induction of autophagy, which ...

CCDC50 suppresses NLRP3 inflammasome activity by mediating ...

Biasizzo M, Kopitar‐Jerala N (2020) Interplay between NLRP3 inflammasome and autophagy. Front Immunol 11: 591803. Crossref · PubMed · Web of ...

Crosstalk between Autophagy and Inflammasomes - SpringerLink

Inflammasome and Autophagy Regulation: A Two-way Street

Interplay Between NLRP3 Inflammasome and Autophagy · Monika BiasizzoN. Kopitar-Jerala. Biology, Medicine. Frontiers in Immunology. 2020. TLDR. Inflammasome ...