Interpretation of subgroup analyses in systematic reviews

Interpretation of subgroup analyses in systematic reviews: A tutorial

We explain the importance of interpreting subgroup analyses, and demonstrate how to interpret subgroup analyses using theoretical examples and a real-life ...

Interpretation of subgroup analyses in systematic reviews_ A tutorial

Many systematic reviews use a statistical technique called meta- analysis to combine individual study results to obtain a pooled treat- ment ...

9.6.2 What are subgroup analyses?

Subgroup analyses involve splitting all the participant data into subgroups, often so as to make comparisons between them.

Statistical Considerations for Subgroup Analyses - PMC

Unlike confirmatory subgroup analysis, exploratory subgroup analyses are intended to obtain preliminary evidence and to generate hypotheses for future ...

Enhancing the Interpretation of Continuous Outcomes and ...

Enhancing the Interpretation of Continuous Outcomes and Subgroup Analyses in Systematic Reviews—Reply · 1. Zhou T, Luo Y, Xiong W, Meng Z, ...

How to understand subgroup analysis in clinical studies

personalized medicine and precision oncology, subgroup analysis seems a valuable tool for optimizing treatment choices. Page 4 ...

Chapter 10: Analysing data and undertaking meta-analyses

Meta-analysis is the statistical combination of results from two or more separate studies. Potential advantages of meta-analyses include an improvement in ...

A systematic review of subgroup analyses in randomised clinical ...

Subgroup analyses are frequently used to assess heterogeneity of treatment effects in randomised clinical trials. Inconsistent, improper and ...

MSU Web Clinic October 2022: Interpretation of subgroup analyses

interpretation of subgroup analyses. Each month, Cochrane's Methods Support Unit https://methods.cochrane.org/about/me... invites Cochrane ...

When to believe a subgroup analysis: revisiting the 11 criteria - Nature

The former is credible if planned based on a prespecified hypothesis, if there is a justified direction of the overall and subgroup effect, and ...

Three simple rules to ensure reasonably credible subgroup analyses

Interpretation of a subgroup analysis is analogous to rigorously interpreting a diagnostic test. Before ordering a diagnostic test, a clinician ...

Interpretation of subgroup analyses in systematic reviews: A tutorial

Authors of systematic reviews may perform subgroup analyses to investigate how treatment effect varies across different subgroups of patients or ...

How to Use a Subgroup AnalysisUsers' Guide to the Medical Literature

Guidelines for Interpreting Subgroup Analyses ... fect (Box 2) Most subgroup analyses from systematic reviews are limited by between-study comparisons.

A meta-epidemiological study of subgroup analyses in cochrane ...

Of 39 Cochrane reviews identified, 17 met inclusion criteria (including 168 reports of 127 randomized trials) and the majority (16; 94.1%) ...

Reporting and interpretation of subgroup analyses in heart failure ...

Subgroup analysis aims to determine whether the overall treatment effect varies across different patient characteristics. Subgroup analyses may ...

Enhancing the Interpretation of Continuous Outcomes and ...

4. Richardson M, Garner P, Donegan S. Interpretation of subgroup analyses in systematic reviews: a tutorial. Clin Epidemiol Glob Health ...

Interpreting a Subgroup Analysis: Is There a Real Effect? - YouTube

Comments2 ; Evaluating a Subgroup Analysis: Was it Designed Properly? Terry Shaneyfelt · 4.9K views ; Forest Plot Interpretation - Clearly ...

Interpretation of Subgroup Effects in Published Trials

This article discusses 3 important issues regarding the analysis and interpretation of existing trials or systematic reviews that report on treatment effect ...

Age-treatment subgroup analyses in Cochrane intervention reviews

However, individual subgroup analyses in randomized controlled trials are often not prespecified, adjusted for multiple testing, or conducted ...

The influence of study characteristics on reporting of subgroup ...

We defined a subgroup analysis as a statistical analysis that explored whether effects of the intervention (experimental v control) differed ...