Intracellular adenosine regulates epigenetic programming in ...

We show here that hypoxia lowered the expression of ADK and increased the levels of intracellular adenosine in human endothelial cells.

Intracellular adenosine regulates epigenetic programming ... - PubMed

The nucleoside adenosine is a potent regulator of vascular homeostasis, but it remains unclear how expression or function of the adenosine-metabolizing ...

Intracellular adenosine regulates epigenetic programming in ... - NCBI

Impact. This study provides valuable new insights into the epigenetic control of pro‐angiogenic factors by intracellular adenosine and implies ...

Intracellular adenosine regulates epigenetic programming in ...

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis · Abstract · Files and links (1) · Metrics · Details · Portal ...

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Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis · Abstract and Figures · Supplementary ...

Intracellular adenosine regulates epigenetic programming in ... - Scite

Supporting: 2, Mentioning: 58 - The nucleoside adenosine is a potent regulator of vascular homeostasis, but it remains unclear how expression or function of ...

Intracellular adenosine regulates epigenetic programming in ...

Based on these findings, we propose that ADK downregulation-induced elevation of intracellular adenosine levels in endothelial cells in the setting of hypoxia ...

Intracellular adenosine regulates epigenetic ... - Altmetric

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. Overview of attention for article published in EMBO ...

Intracellular adenosine regulates epigenetic programming in ...

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis · Searching Remote Databases, Please Wait.

Your search: "author:Huo, Yuqing" - eScholarship

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis · Xu, Yiming;; Wang, Yong;; Yan, Siyuan;; Zhou, Yaqi; ...

Regulation of endothelial intracellular adenosine via ... - Nature

As a low capacity, high affinity enzyme with a much lower Michaelis constant (1 mM), ADK is regarded as the principal enzyme in regulating ...

Adenosine kinase and cardiovascular fetal programming in ...

AK is an enzyme that produces AMP from adenosine and ATP. Its activity is regulated by various factors, including nitric oxide (NO), intracellular pH (pHi), d- ...

Citations to Epigenetic changes induced by adenosine ... - JCI

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. Y Xu, Y Wang, S Yan, Y Zhou, Q Yang, Y Pan, X Zeng, X ...

Accumulation of endogenous adenosine improves cardiomyocyte ...

Here we investigated the role of cellular adenosine in epigenetic regulation on cardiomyocyte gene expression, glucose metabolism and tolerance to I/R. Evans ...

Adenosine Kinase on Deoxyribonucleic Acid Methylation - Frontiers

New insights regarding the potential role of the adenosine receptor-independent pathway in the epigenetic modulation of DNA methylation offer the possibility of ...

Emerging roles of dysregulated adenosine homeostasis in brain ...

DNA methylation, a type of epigenetic modification, controls gene expression by preventing the binding of transcription factors to the promoter ...

Epigenetic Regulation of Endothelial Cell Function by Nucleic Acid ...

In addition to oxygen levels, vascular perfusion and direction of blood flow are known to regulate DNA methylation and gene expression in ECs, ...

Epigenetic regulation in metabolic diseases: mechanisms ... - Nature

Chromatin remodelling complexes can regulate gene expression by utilising the energy of adenosine triphosphate (ATP) hydrolysis to change the ...

Enzymatic deamination of the epigenetic nucleoside N 6

N6-methyladenosine (m6A) modification is the most extensively studied epigenetic modification due to its crucial role in regulating an array of ...

Citations to Flow-dependent epigenetic DNA methylation regulates ...

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. Y Xu, Y Wang, S Yan, Y Zhou, Q Yang, Y ...