- Introduction to cryo|EM model rebuilding in ISOLDE🔍
- Tutorials — ISOLDE 1.6.0 documentation🔍
- Rebuilding a cryo|EM model using ISOLDE🔍
- Introduction to interactive low|resolution model building with ISOLDE🔍
- General model building workflow🔍
- Model Building & Refinement with ChimeraX/Isolde 2/3🔍
- Exploring generative atomic models in cryo|EM reconstruction🔍
- Deriving and refining atomic models in crystallography and cryo|EM🔍
Introduction to cryo|EM model rebuilding in ISOLDE
Introduction to cryo-EM model rebuilding in ISOLDE - GitHub Pages
This highlights the reason ISOLDE exists: atomic model building is a difficult challenge even in quite good density, and overcoming it requires as much ...
Tutorials — ISOLDE 1.6.0 documentation - GitHub Pages
Introductory¶. Introduction to crystallographic model rebuilding in ISOLDE · Introduction to cryo-EM model rebuilding in ISOLDE · Dealing with severe clashes ...
Rebuilding a cryo-EM model using ISOLDE - YouTube
Complete, un-edited capture of the interactive rebuilding of 3j9d (a 747-residue model built into 3.3 Angstrom cryo-EM data: ...
ISOLDE: a physically realistic environment for model building into ...
ISOLDE is an interactive molecular-dynamics environment for rebuilding models against experimental cryo-EM or crystallographic maps ... Overview of the ISOLDE ...
Introduction to interactive low-resolution model building with ISOLDE
Tristan Croll presents ISOLDE (Interactive Structure Optimisation by Local Direct Exploration), a new environment that brings together ...
A demonstration of using ISOLDE to improve models from structural biology data, by Tristan Croll (Cambridge). Recorded at the CCPBioSim ...
General model building workflow - Wiedenheft Lab
-2021 Phenix Workshop on Cryo-EM Map improvement: Sharpening ... Isolde tutorial. Useful Strategies to accelerate COOT and prevent ...
Model Building & Refinement with ChimeraX/Isolde 2/3 - YouTube
I recorded this video when I was a postdoc in the Marlovits lab at the CSSB in Hamburg. The basic idea behind this video was to provide a ...
ISOLDE: a physically realistic environment for model building into ...
ISOLDE is an interactive molecular-dynamics environment for rebuilding models against experimental cryo-EM or crystallographic maps and reinforces the need ...
Exploring generative atomic models in cryo-EM reconstruction - arXiv
1 Introduction. Single particle cryo-electron microscopy (cryo-EM) is ... from an atomic model into cryo-EM reconstruction. By ...
Deriving and refining atomic models in crystallography and cryo-EM
In structural biology, deriving and refining atomic models into maps obtained from X-ray crystallography or cryo electron microscopy (cryo-EM) is essential ...
ISOLDE: a physically realistic environment for model building into ...
ISOLDE is an interactive molecular-dynamics environment for rebuilding models against experimental cryo-EM or crystallographic maps.
ISOLDE: a physically-realistic environment for model building into ...
Using the recently-described 3.8Å cryo-EM structure of the eukaryotic minichromosome maintenance (MCM) helicase complex as a case study, here I demonstrate how ...
Modelling structures in cryo-EM maps - ScienceDirect.com
Approaches to the structure determination and modelling of macromolecular assemblies depend on the resolution of their cryo-EM map.
Building & refinement. (Chimera, COOT, ISOLDE, etc…) Page 6. Yip, K.M., Fischer, N., Paknia, E. et al. Atomic-resolution protein structure determination by cryo ...
Automated model building and protein identification in cryo-EM maps
By introducing objectivity in the model-building ... Croll, T. I. Isolde: a physically realistic environment for model building into low- ...
Integrating model simulation tools and cryo‐electron microscopy
To address such problems, many computational methods have been developed for cryo-EM map reconstruction and atomistic model building. Here, we ...
Structural interpretation of cryo-EM image reconstructions
In this review, we discuss the practiced work-flow from the cryo-EM image reconstruction to the atomic model. We give an overview of (i) resolution ...
(IUCr) Putting AlphaFold models to work with phenix ...
These confidence metrics are further used in ISOLDE to weight torsion and atom–atom distance restraints, allowing the complete AlphaFold model to be ...
Accurate model and ensemble refinement using cryo-electron ...
Here we introduce EMMIVox, a Bayesian inference approach to determine single-structure models as well as structural ensembles from cryo-EM maps.