Isolation of psychedelic|responsive neurons underlying anxiolytic ...

Isolation of psychedelic-responsive neurons underlying anxiolytic ...

We labeled psychedelic-responsive mPFC neurons with an excitatory channelrhodopsin to enable their targeted manipulation. We found that ...

Anti-anxiety and hallucination-like effects of psychedelics mediated ...

The anti-anxiety andhallucination-inducing qualities of psychedelic drugs work through different neural circuits, according to research using a ...

Neuroscience News on X: "“Isolation of psychedelic-responsive ...

Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states” by David E. Olson et al.

Psychedelic-Inspired Anxiety Treatments Could Avoid Hallucinations

The team's findings indicate that while 5-HT2AR-expressing cells initiate the effect, other neurons in the mPFC are subsequently activated, ...

Institute for Psychedelics and Neurotherapeutics on X: "Exciting new ...

... anti-anxiety and hallucinogenic effects of #psychedelics ... Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states.

Psychedelics excite cells in hippocampus to reduce anxiety

The findings show the psychedelic DOI (2,5-dimethoxy-4-iodoamphetamine) lessened anxiety in mice and rats while activating the ventral ...

Prolonged epigenomic and synaptic plasticity alterations following ...

However, the biological substrates and key mediators of psychedelics' enduring action remain unknown. Here, we show that a single administration of the ...

Psychedelic drug DOI activates specific brain neurons to ease anxiety

The psychedelic DOI reduces anxiety by activating specific interneurons in the ventral hippocampus without causing hallucinations, ...

Neural mechanisms underlying psilocybin's therapeutic potential

Thus, we integrate information about the neural bases for oscillatory activity generation with the accumulating evidence about psychedelic drug effects on ...

New Research Reveals How Psychedelics May Help Alleviate Anxiety

The study, published in the journal Neuron, focuses on the effects of DOI (2,5-dimethoxy-4-iodoamphetamine), a psychedelic similar to LSD, ...

Psychedelics excite cells in hippocampus to reduce anxiety

A classic psychedelic was found to activate a cell type in the brain of mice and rats that silences other neighboring neurons, ...

Psychedelic Drugs in Biomedicine - ScienceDirect.com

Psychedelic Drugs for Treatment of Anxiety and Depression. As a result of the ... Here, we focus on four classes of underlying effects of psychedelics ...

Breakthrough Study Pinpoints Brain Region Where Psychedelics ...

The psychedelic DOI reduces anxiety by targeting specific neurons in the ventral hippocampus, offering a path to new treatments that avoid hallucinatory side ...

High-resolution tracking of unconfined zebrafish behavior reveals ...

Serotonergic psychedelics are emerging therapeutics for psychiatric disorders, yet their underlying mechanisms of action in the brain remain ...

Psilocybin-enhanced fear extinction linked to bidirectional ...

“Delayed Anxiolytic-Like Effects of Psilocybin in. Male Mice ... “Cellular Rules. Underlying Psychedelic Control of Prefrontal Pyramidal. Neurons.” Preprint.

Neural Mechanisms of Resting-State Networks and the Amygdala ...

Psilocybin is a serotonergic psychedelic and the main psychoactive compound found in numerous species of mushrooms that have been used to alter ...

Effect of chemically synthesized psilocybin and psychedelic ... - Nature

In conclusion, our synaptic protein findings suggest that PME has a more potent and prolonged effect on synaptic plasticity than PSIL. Our ...

Neural Mechanisms and Psychology of Psychedelic Ego Dissolution

Neuroimaging studies of psychedelics have advanced our understanding of hierarchical brain organization and the mechanisms underlying their ...

Transient Elevation of Plasma Glucocorticoids Supports Psilocybin ...

Using rodents, both time-bound manipulation of glucocorticoid concentrations and assessment of anxiety-like behaviors can be achieved. Here, 3 ...

How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its ...

... Psychedelics as Neuroplasticity “Wedge” 01:16:53 Positive Psychedelic Journeys, Unity, “Oceanic Boundlessness” 01:25:23 “Bad Trips”, Anxiety ...