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Lab for Neglected Tropical Disease Drug Discovery – Just another ...


Lab for Neglected Tropical Disease Drug Discovery – Just another ...

The main thrust of our program is to identify biological targets in pathogenic parasites that are homologous to biological targets in humans that have been ...

Lori Ferrins - Lab for Neglected Tropical Disease Drug Discovery

... neglected diseases that are often overlooked by the for-profit pharmaceutical industry. The lack of an effective treatment, or access to one, means that ...

Innovation in neglected tropical disease drug discovery and ...

Many basic research findings have yet to find their way to drug discovery ... Another example of the open source model relates to the Tres Cantos Open Lab ...

Research - THE McNAMARA LAB

... an annual basis. However, the impact of these neglected tropical disease (NTDs), and others, cannot be simply measured with these metrics. Importantly, NTDs ...

Pharmacological Profiles of Neglected Tropical Disease Drugs

Another important step in broadening the field of NTD research ... To align research activities between pharmaceutical companies, research labs ...

Research Activities on NTDs - Astellas Pharma Inc.

... different trademarks, for different indications, or in different ... *1 Neglected Tropical Diseases Drug Discovery Booster: A consortium launched by the Drugs ...

New hope for drug discovery in African sleeping sickness

Pollastri, who runs Northeastern's Laboratory for Neglected Disease Drug Discovery ... other's work on neglected tropical diseases. This new ...

Improving Collaborations for Neglected Tropical Diseases

... yet only a tiny fraction of all drug discovery efforts is focused on this. There is little sharing of data across labs working in this area, leading to ...

Machine learning and drug discovery for neglected tropical diseases

We hope to save time and cut costs by using machine learning in the screening process and only testing compounds in the lab which are predicted ...

High Throughput and Computational Repurposing for Neglected ...

This is anticipated to assist companies to focus on developing treatments for these diseases. Another way to overcome the challenges of NTD drug development is ...

ChEMBL-NTD - GitBook

ChEMBL-NTD is largely a subset of the data in the free medicinal chemistry and drug discovery database ChEMBL. It is intended for NTD data that ...

Advances in Drug Discovery for Neglected Tropical Diseases

... pharmaceutical industries in funding research on these diseases. In fact, only 16 drugs were approved by the United States Food and Drug ...

Neglected tropical diseases - World Health Organization (WHO)

Neglected tropical diseases (NTDs) are a diverse group of conditions 1 caused by a variety of pathogens (including viruses, bacteria, parasites, fungi and ...

Michael Pollastri - Developing a New Model for Data ... - YouTube

Michael Pollastri - Developing a New Model for Data Sharing in Neglected Disease Drug Discovery. 106 views · 9 years ago ...more. The ...

Finding New Collaboration Models for Enabling Neglected Tropical ...

... Neglected Tropical Disease Drug Discovery. PLoS Negl Trop Dis 8 ... often adopt the “closed” drug discovery process, simply by habit or an ...

Challenges and recent progress in drug discovery for tropical diseases

... drug-discovery programme for an infectious disease. Fig ... but are absent for many other diseases, hampering the drug-discovery process.

In treating neglected tropical diseases, chemistry expert Michael ...

In treating neglected tropical diseases, chemistry expert Michael Pollastri says "The best way to discover a new drug is to start with an ...

Drug Discovery for Neglected Diseases: Molecular Target-Based ...

The focus will be on human African trypanosomiasis (HAT) but will be of relevance for other neglected tropical diseases. Target-Based ...

What Drug Researchers Can Learn From a Kenyan Clinic - PBS

... yet there are disproportionally few research labs working to discover new drugs for them. ... neglected disease drug discovery. Using this system, ...

Five ways innovation is changing the fight against Neglected ...

For too long the medical needs of people affected by neglected tropical diseases have been ignored. But there are reasons for hope. In some places we can ...