Largest genome|wide association study ever uncovers nearly all ...

Largest genome-wide association study ever uncovers nearly all ...

By analyzing data from nearly 5.4 million people, Broad researchers have identified more than 12000 genetic variants that influence height.

Largest GWAS Maps Variation in Human Height - NCI

The international consortium known as GIANT published results from the largest-known genome-wide association study (GWAS)—nearly 5.4 million ...

Harvard University on X: "In the largest study of its kind to date ...

Largest genome-wide association study ever uncovers nearly all genetic variants linked to height. By analyzing data from nearly 5.4 million people, Broad ...

GIANT study finds rare, but influential, genetic changes related to ...

GWAS are good at finding common genetic variants, but nearly all of the identified variants alter height by less than 1 mm (less than 1/20 of an ...

Meta-analysis of genome-wide association studies for height and ...

In total, our sample size reaches ∼700000, which is unprecedented for GWAS of these traits. The present study is part of a larger effort led by the GIANT ...

Genome-wide association studies | Nature Reviews Methods Primers

Ideally, WGS — which determines nearly every genotype of a full genome — is preferred over WES and microarrays, and is expected to become the ...

Insights and Implications of Genome-Wide Association Studies of ...

With ever-increasing numbers of loci, curated gene sets, gene expression profiles, epigenetic datasets, and improvement in current computational algorithms, ...

Reaching new heights in largest ever genome study - UQ News

Dr Loic Yengo and Professor Peter Visscher from UQ's Institute for Molecular Bioscience have worked with 600 researchers in the largest-ever ...

GIANT study finds rare, but influential, genetic changes related to ...

GWAS are good at finding common genetic variants, but nearly all of the identified variants alter height by less than 1 mm (less than 1/20 of an ...

Largest ever diabetes genetics study uncovers mechanisms behind ...

The researchers used an approach called genome-wide association analysis, which involved scanning the complete set of DNA (the genome) from ...

15 years of GWAS discovery: Realizing the promise - ScienceDirect

The fundamental promise of the genome-wide association study (GWAS) experimental design was that polymorphisms could be detected that are associated with ...

Massive international study uncovers genes involved in heart disease

Scientists link dozens of new genome sites to coronary artery disease risk and pioneer a powerful method for illuminating the biological ...

New concerns raised over value of genome-wide disease studies

And Joel Hirschhorn, a human geneticist at Children's Hospital Boston in Massachusetts, says that not all hits uncovered by very large GWAS are ...

Largest genome study provides insight into the genetics of human ...

Researchers have discovered more than 12,000 genetic variants associated with human height in the largest known genome-wide study.

Scientists stack up new genes for height - EurekAlert!

... largest consortium of researchers to ever study the trait. The ... In this large study, forty-six smaller genome-wide association studies ...

10 Years of GWAS Discovery: Biology, Function, and Translation

Here we review the remarkable range of discoveries that genome-wide association studies (GWASs) have facilitated in population and complex-trait genetics.

GWAS of More Than Five Million People Uncovers Thousands of ...

NEW YORK — Through a genome-wide association study of 5.4 million ... nearly all the variants that influence height may have been found.

Cross-ancestry meta-analysis of opioid use disorder uncovers novel ...

Sanger Institute (which includes all samples from 1000 Genomes Project phase 3, ... A large-scale genome-wide association study meta-analysis of cannabis use ...

Largest genome-wide association study ever uncovers nearly all ...

HomeNewsBoston Cambridge Biotech Trending NewsLargest genome-wide association study ever uncovers nearly all genetic variants linked to height ...

CNest: A novel copy number association discovery method ...

Copy number variation (CNV) is known to influence human traits, having a rich history of research into com- mon and rare genetic disease, ...