Leveraging the Lymphatic System for Cancer Immunotherapy

Over the past decade, our understanding of the role of the lymphatic vasculature in tumor progression has evolved from it being a passive ...

Leveraging the Lymphatic System for Cancer Immunotherapy - PMC

The specific expansion of LN regulatory T cells, as well as many other mechanisms of LN maladaptation to tumor drainage, are likely candidates for immune ...

In this review, I dissect the promise and challenge of engaging the lymphatic system for therapy and suggest important avenues for future investigation and ...

Advanced Drug Delivery Reviews | Drugging the lymphatic system

Drugging the lymphatic system: An emerging opportunity for cancer · Last update 12 May 2022 · A collection of 9 articles · Drugging the lymphatic system: An ...

Drugging the lymphatic system: An emerging opportunity for cancer ...

Porter, Lymph-directed immunotherapy – Harnessing endogenous lymphatic distribution pathways for enhanced therapeutic outcomes in cancer, Advanced Drug.

Leveraging the Lymphatic System for Cancer Immunotherapy.

Immune Potential Untapped: Leveraging the Lymphatic System for Cancer Immunotherapy. · Cancer Immunology Research, July 2022 · 10.1158/2326-6066.cir-22-0266.

Immune Potential Untapped: Leveraging the Lymphatic System for ...

Immune Potential Untapped: Leveraging the Lymphatic System for Cancer Immunotherapy. Check for available services. Send to. QR. Mendeley. Export BibTeX.

Immune Potential Untapped: Leveraging the Lymphatic System for ...

Immune Potential Untapped: Leveraging the Lymphatic System for Cancer Immunotherapy. https://doi.org/10.1158/2326-6066.cir-22-0266 ·. Видання: Cancer ...

Lymph node targeting for immunotherapy

In addition to lymphatic drainage, antigens and immune cells can also enter lymph nodes via the high endothelial venules (HEVs). As the primary ...

Lymphatic system regulation of anti-cancer immunity and metastasis

However, recent studies have also characterized previously unrecognized roles for tumor-draining lymph nodes (TDLNs) in cancer immunotherapy response, including ...

Therapeutic Immunomodulation of Tumor-Lymphatic Crosstalk via ...

Engineered drug delivery systems that enhance intratumoral immunotherapy by improving drug delivery to both the tumor and lymph nodes are also ...

Meet Dr. Amanda Lund, One of the New CRI Lloyd J. Old STARs

Yes, absolutely. First, we realized that by manipulating lymphatic vessels, we could manipulate immune responses against cancer. We found that ...

Can Lymph Nodes Boost the Success of Cancer Immunotherapy?

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

Tumor-draining lymph nodes: opportunities, challenges, and future ...

Tumor-draining lymph nodes (TDLNs) are potential immunotherapy targets that could expand the population of patients with colorectal cancer (CRC) who may ...

The tumor-draining lymph node as a reservoir for systemic immune ...

Lymphatic transport facilitates antigen presentation in tumor-draining lymph nodes (tdLNs), and priming against tumor-associated antigen ...

Lymph-directed immunotherapy – harnessing endogenous ...

... cancers that historically, were difficult to treat. A unifying concept in cancer immunotherapy is the activation of the immune system to mount an attack on ...

Publications - Laboratory of Lymphatic Immunobiology

Lund, AW. Immune Potential Untapped: Leveraging the Lymphatic System for Cancer Immunotherapy. 2022. Cancer Res Immunol. doi.org/10/1158/2326-6066.

Leveraging the Dynamic Immune Environment Triad in Patients with ...

During the anti-tumour response to breast cancer, the primary tumour, the peripheral blood, and the lymph nodes each play unique roles. Immunological features ...

Application of Nano-Delivery Systems in Lymph Nodes for Tumor ...

Immunotherapy has become a promising research “hotspot” in cancer treatment. “Soldier” immune cells are not uniform throughout the body; they ...

Lymph-directed immunotherapy – Harnessing endogenous ...

... cancer | The advent of immunotherapy has revolutionised the treatment of some cancers. Harnessing the immune system to improve tumour cell killing is now ...