Lineage|defined leiomyosarcoma subtypes emerge years before ...

Lineage-defined leiomyosarcoma subtypes emerge years before ...

Leiomyosarcomas (LMS) are genetically heterogeneous tumors differentiating along smooth muscle lines. Currently, LMS treatment is not ...

(PDF) Lineage-defined leiomyosarcoma subtypes emerge years ...

Finally, by phylogenetic reconstruction, we present evidence that clones seeding lethal metastases arise decades prior to LMS diagnosis. Heterogeneity in ...

Lineage-defined leiomyosarcoma subtypes emerge years before ...

Abstract Leiomyosarcomas (LMS) are genetically heterogeneous tumors differentiating along smooth muscle lines. Currently, LMS treatment is not informed by ...

Lineage-defined leiomyosarcoma subtypes emerge years before ...

Analysis of LMS heterogeneity and molecular LMS subtypes using genomics and transcriptomics finds origins in distinct lineages and associations with ...

Lineage-defined leiomyosarcoma subtypes emerge years before ...

Leiomyosarcomas (LMS) are genetically heterogeneous tumors differentiating along smooth muscle lines. Currently, LMS treatment is not informed by molecular ...

Lineage-defined leiomyosarcoma subtypes emerge years before ...

Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival ... Clinically relevant molecular subtypes in leiomyosarcoma.

Lineage-defined leiomyosarcoma subtypes emerge years before ...

Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival. Anderson, N. D, Babichev, Y., Fuligni, F., Comitani, ...

Discovery of molecular subtypes in leiomyosarcoma through ...

Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We employed integrative molecular profiling to ...

Molecular subtypes of leiomyosarcoma: Moving toward a consensus

Leiomyosarcoma (LMS) is one of the most common soft tissue sarcoma (STS) subtypes, accounting for up to 20% of STS diagnoses.

The biology and treatment of leiomyosarcomas - ScienceDirect.com

N.D. Anderson, et al. Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival. Nat. Commun., 12 (1) (2021), pp ...

Targeting the Molecular and Immunologic Features of ... - MDPI

Leiomyosarcoma (LMS) is a rare, aggressive mesenchymal tumor with smooth muscle differentiation. LMS is one of the most common histologic subtypes of soft ...

Drivers of genomic loss of heterozygosity in leiomyosarcoma are ...

Leiomyosarcoma (LMS) is a rare, aggressive, mesenchymal tumor. Subsets of LMS have been identified to harbor genomic alterations associated ...

Home Page - Leiomyoarcoma.info

This publication is yet another compass for the Roundtable focus workgroups: Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and ...

Molecular subtypes of leiomyosarcoma: Moving toward a consensus

tissue sarcoma (STS) subtypes, accounting for up to ... Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine ...

Therapeutic advances in leiomyosarcoma - Frontiers

This is of importance as many clinical trials for LMS are designed to include all anatomical subtypes. From an analysis of 1115 LMS tumors, ...

Developing Novel Genomic Risk Stratification Models in Soft Tissue ...

, et al . Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival . Nat Commun. 2021. ;. 12. : 4496 . Google ...

Leiomyosarcoma - Surgical Oncology Clinics

16. Anderson, N.D. ∙ Babichev, Y. ∙ Fuligni, F. ... Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.

The Future of Targeted Therapy for Leiomyosarcoma

Lineage-Defined Leiomyosarcoma Subtypes Emerge Years before Diagnosis and Determine Patient Survival. Nat. Commun. 2021, 12, 4496. [CrossRef] ...

New developments in the pathology and molecular biology of ...

41. Anderson, N.D. ∙ Babichev, Y. ∙ Fuligni, F. ... Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient ...

Discovery of molecular subtypes in leiomyosarcoma through ...

Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We used integrative molecular profiling to ...