Lipid Rafts Play a Role in Immune Cell Activation

lipid rafts play a role in immune cell activation - PubMed

Floating the raft hypothesis: lipid rafts play a role in immune cell activation.

Lipid rafts in immune signalling: current progress and future ...

Role of lipid rafts in lymphocyte activation · Immune cell activation is required for defence against microbes and several reports suggest a crucial role of ...

Lipid Rafts Play a Role in Immune Cell Activation - CORE

Raft Translocation in Immune Cell Activation. In resting cells, the MIRRs are excluded from lipid rafts, as are most plasma membrane proteins including the ...

The Functional Roles of Lipid Rafts in T Cell Activation, Immune ...

The first appearance of lipid rafts, or lipid rafts-like structure, was occasionally observed by cryo-electronic microscopy in 1980s as ...

Lipid rafts and their roles in T-cell activation - ScienceDirect.com

Lipid rafts are defined as detergent-resistant membrane microdomains of specific lipid and protein composition. They are involved in many aspects of cell ...

Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review

Cytokines are soluble factors released by cells in response to infection and inflammation and they are key modulators of the immune system. Cytokine receptors ...

Review Lipid rafts in T cell signalling and disease - ScienceDirect.com

A large number of studies report on lipid rafts having a key role in receptor signalling and activation of lymphocytes. In T cells, lipid raft involvement ...

Editorial: Role of Lipid Rafts in Anti-microbial Immune Response

Since pathogens can exploit lipid rafts for cellular interaction via direct contact or virulence factors, disruption or restriction of membrane raft formation ...

The regulatory roles of glycosphingolipid‐enriched lipid rafts in ...

Lipid rafts formed by glycosphingolipids (GSLs) on cellular membranes play important roles in innate and adaptive immunity.

Full article: Lipid rafts in lymphocyte activation and migration (Review)

At the plasma membrane, T cell polarization is accompanied by assemblies of specialized lipids with the characteristics of 'lipid rafts'. Under ...

Mediators of innate immune recognition of bacteria concentrate in ...

Lipid raft integrity is essential for LPS-cellular activation, since raft-disrupting drugs, such as nystatin or MCD, inhibit LPS-induced TNF-α secretion. Our ...

Recruitment of TNF Receptor 1 to Lipid Rafts Is Essential for TNFα ...

Interfering with lipid raft organization not only abolishes ubiquitylation but switches TNFα signaling from NF-κB activation to apoptosis. We suggest that lipid ...

Visualizing Lipid Raft Dynamics and Early Signaling Events during ...

These B-cell cytonemes are rich in lipid rafts and actin filaments, suggesting that they might play a role in long-range communication and/or ...

The role of lipid rafts in signalling and membrane trafficking in T ...

As in epithelial cells, rafts are used also as vesicular carriers for membrane trafficking in T lymphocytes. Furthermore, there are potential ...

Location, Location, Location: Is Membrane Partitioning Everything ...

Lipid rafts are thought to provide a means to explain the spatial segregation of certain signalling pathways emanating from the cell surface.

Dynamic changes in the mobility of LAT in aggregated lipid rafts ...

To elucidate the process of lipid raft aggregation during T cell activation, we analyzed the dynamic changes of a raft-associated protein, linker for activation ...

Cholesterol, lipid rafts, and disease - JCI

Lipid rafts are dynamic assemblies of proteins and lipids that float freely within the liquid-disordered bilayer of cellular membranes.

A Role for Lipid Rafts in Immune Cell Signaling | Request PDF

... The lipid raft hypothesis suggests that there is a degree of self-organization within the cell membranes such that dynamic microenvironments are created ...

Lipid rafts and their roles in T-cell activation - OUCI

Horejsi, The roles of membrane microdomains (rafts) in T cell activation, Immunol. · Brown, Structure and function of sphingolipid- and cholesterol-rich membrane ...

Lipid rafts as viral entry routes and immune platforms - Europe PMC

The raft-associated protein cav-1 can inhibit eNOS in endothelial cells and the subsequent production of NO, which plays an important role in inflammation.