Localized epigenetic silencing of a damage|activated WNT ...

Localized epigenetic silencing of a damage-activated WNT ... - eLife

Localized epigenetic silencing of damage-responsive enhancers can therefore restrict regenerative capacity in maturing organisms without compromising gene ...

Localized epigenetic silencing of a damage-activated WNT ...

We demonstrate that damage-responsive expression of both genes requires a bipartite enhancer whose activity declines during L3. Within this ...

Localized epigenetic silencing of a damage-activated WNT ...

Localized epigenetic silencing of damage-responsive enhancers can therefore restrict regenerative capacity in maturing organisms without compromising gene ...

Localized epigenetic silencing of a damage-activated WNT ... - eLife

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs · Cite · Share · Comment ...

Localized epigenetic silencing of a damage-activated WNT ...

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs. Share this: Twitter · LinkedIn.

Localized epigenetic silencing of a damage-activated WNT ...

Request PDF | Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs | Many organisms ...

Localized epigenetic silencing of a damage-activated WNT ...

Dive into the research topics of 'Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs'.

Localized epigenetic silencing of a damage-activated WNT ... - OUCI

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs · Abstract · List of references.

Localized epigenetic silencing of a damage-activated WNT ...

Many organisms lose the capacity to regenerate damaged tissues as they mature. Damaged Drosophila imaginal discs regenerate efficiently early in the third ...

(PDF) Localized epigenetic silencing of a damage-activated WNT ...

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs ; Journal Article•DOI · +1 more ...

Localized epigenetic silencing of a damage-activated WNT ...

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs. Harris RE et al. eLife. 2016 Feb ...

Epigenetic regulation of the Hedgehog and Wnt pathways in cancer

Epigenetic silencing of SUFU could therefore result in an increase of GLI protein level. Activation of the Hh pathway leads to inhibition of SUFU and the GLI ...

Wnt/β‑catenin pathway activation and silencing of the APC gene in ...

In addition, β-catenin has been observed to be localized ... epigenetic silencing inhibitors reduced the abnormal activation of the Wnt pathway in ...

Frequent epigenetic inactivation of Wnt antagonist genes in breast ...

Although mutation of APC or CTNNB1 (β-catenin) is rare in breast cancer, activation of Wnt signalling is nonetheless thought to play an ...

SUV39H2 epigenetic silencing controls fate conversion of epidermal ...

Notable examples supporting Wnt activation were a >100-fold up-regulation ... R. Nusse . 2013 . A localized Wnt signal orients asymmetric ...

Loss of epigenetic information as a cause of mammalian aging: Cell

To localize I-PpoI expression and DNA damage ... Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and ...

PTGS is dispensable for the initiation of epigenetic silencing of an ...

... local transcriptional and epigenetic landscape · 10.1101/2023.06 ... Epigenetic Collateral Damage in Arabidopsis · 10.1101/2021.04 ...

Epigenetic Regulation of the Wnt/β-Catenin Signaling Pathway in ...

Silencing the Wnt antagonistic ... (A) β-catenin can form complexes with different epigenetic modulators and activate gene expression upon Wnt activation.

Epigenetic gene silencing in cancer: the DNA hypermethylome

In general, histone deacetylation leads to gene silencing, while histone acetylation leads to gene activation. ... localized changes in chromatin architecture. ,.

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt ...

Request PDF | Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf V600E-Induced Tumorigenesis Article Aging-like ...