Long Noncoding RNA|Directed Epigenetic Regulation of Gene ...

Long Noncoding RNA-Directed Epigenetic Regulation of Gene ...

Experience-dependent expression of lncRNAs plays an important role in the epigenetic regulation of adaptive behavior, and the perturbation ...

Gene regulation by long non-coding RNAs and its biological functions

Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene ...

Long noncoding RNA-directed epigenetic regulation of gene ... - NCBI

In summary, we have shown that the down-regulation of Gomafu lncRNA drives anxiety-like behavior. We further propose a novel role for lncRNAs ...

Non-coding RNAs as regulators in epigenetics (Review)

In recent years, a large number of studies have shown that non-encoding RNAs play a significant role in epigenetic modification and can regulate ...

Long Noncoding RNA-Directed Epigenetic Regulation of Gene ...

Experience-dependent expression of lncRNAs plays an important role in the epigenetic regulation of adaptive behavior, and the perturbation of ...

Long non-coding RNAs: definitions, functions, challenges and ...

lncRNAs also control methylation of a number of non-histone proteins involved in animal cell signalling, gene expression and RNA processing.

Long Noncoding RNA-Directed Epigenetic Regulation of Gene ...

RNA sequencing was used to identify changes in the experience-dependent expression of long noncoding RNAs (lncRNAs) within the medial prefrontal cortex of ...

Long Noncoding RNA-Directed Epigenetic Regulation of Gene ...

RNA sequencing analysis revealed changes in the expression of a significant number of genes related to neural plasticity and stress, as well as the dynamic ...

Behind the scenes: How RNA orchestrates the epigenetic regulation ...

RNA-mediated epigenome regulation. 2.1 Long non-coding RNA-mediated regulation of gene expression. Among the most important mechanisms regulating cell ...

Long Noncoding RNA-Directed Epigenetic Regulation of Gene ...

Our results revealed that Gomafu plays a role in mediating anxiety-like behavior and suggest that this may occur through an interaction with a key member of the ...

Long Non-Coding RNA Epigenetics - MDPI

Many lncRNAs are implicated in gene-regulatory roles such as chromosome dosage compensation, imprinting, transcription, translation, splicing, cell cycle ...

The functional role of long non-coding RNAs and epigenetics

On the contrary, lncRNAs may function to regulate gene expression at both transcriptional and posttranscriptional levels based on both genetic ...

Long noncoding RNA: multiple players in gene expression

Genomic imprinting is an example of epigenetic regulation. As two representative monoallelic, parental-specific noncoding transcripts, Kcnq1ot1 and Airn have ...

Epigenetic coordination of embryonic heart transcription by ... - PNAS

The vast majority of mammalian DNA does not encode for proteins but instead is transcribed into noncoding (nc)RNAs having diverse regulatory functions. The ...

Epigenetic regulation of human non-coding RNA gene transcription

Recent investigations on the non-protein-coding transcriptome of human cells have revealed previously hidden layers of gene regulation relying on regulatory ...

Non-coding RNAs as regulators of gene expression and epigenetics

LncRNAs have been proposed to regulate transcription by recruiting chromatin-remodelling complexes, which in turn mediate epigenetic changes.10 Epigenetics ...

Non-coding RNAs as direct and indirect modulators of epigenetic ...

Ongoing research continues to uncover novel pathways, including the important role of non-protein coding RNA transcripts in epigenetic gene regulation. We know ...

LncRNA Functions as a New Emerging Epigenetic Factor ... - Frontiers

Long non-coding RNA is involved in the adipogenic differentiation of stem cells. Understanding the mechanisms underlying adipogenesis regulation ...

Structure and function of long noncoding RNAs in epigenetic ...

This work focuses on the well-characterized ability for lncRNAs to function as epigenetic modulators, and suggests that lnc RNAs may be part of a broad ...

The multidimensional mechanisms of long noncoding RNA function

Increasingly, studies suggest that lncRNAs regulate gene expression through diverse mechanisms. We review emerging mechanistic views of lncRNAs ...