Longitudinal immune profiling of mild and severe COVID|19 reveals ...

Longitudinal immune profiling of mild and severe COVID-19 reveals ...

By profiling mild and severe COVID-19 patients and healthy donors with flow cytometry, we demonstrate that SARS-CoV-2 is associated with broad ...

Longitudinal immune profiling of mild and severe COVID-19 reveals ...

Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool ...

Longitudinal immune profiling of mild and severe COVID-19 reveals ...

Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical ...

Longitudinal analyses reveal immunological misfiring in severe ...

Here we serially analysed immune responses in 113 patients with moderate or severe COVID-19. Immune profiling revealed an overall increase in ...

Longitudinal immune profiling reveals key myeloid signatures ...

Severe COVID-19 disease is associated with immune hyperactivation accompanied by “cytokine storm.” Mann et al. used longitudinal analysis of fresh blood ...

COVID-19 Longitudinal immune profiling reveals dominant epitopes ...

We assessed SARS-CoV-2 immune dynamics up to 180 to 220 days after disease onset in 31 individuals who predominantly experienced moderate symptoms of COVID-19, ...

Longitudinal immune profiling reveals dominant epitopes mediating ...

Longitudinal analysis revealed sustained SARS-CoV-2 spike protein–specific antibodies and neutralizing antibodies in COVID-19 patients, along ...

Longitudinal profiling of respiratory and systemic immune responses ...

Myeloid cells in COVID-19 airways featured hyperinflammatory signatures, and higher frequencies of these cells correlated with mortality and ...

Multi-dimensional and longitudinal systems profiling reveals ...

Here, we longitudinally profiled and integrated more than 150 clinical, laboratory, and immunological parameters of 173 patients with mild to fatal COVID-19.

Extensive longitudinal immune profiling reveals sustained innate ...

COVID-19 differs substantially between individuals, ranging from mild to severe or even fatal. Heterogeneity in the immune response against ...

Longitudinal immune profiling reveals distinct features of COVID-19 ...

Interpretation This is the first detailed longitudinal analysis of COVID-19 patients of varying severity and outcome, revealing common features ...

Single-cell immune profiling reveals distinct immune response in ...

While some individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) present mild-to-severe disease, ...

Longitudinal antibody repertoire in “mild” versus “severe” COVID-19 ...

Limited knowledge exists on immune markers associated with disease severity or recovery in patients with coronavirus disease 2019 (COVID-19) ...

The longitudinal characterization of immune responses in COVID-19 ...

Both SARS-CoV-2 reactive IgA and IgG were detected at T0, concomitantly with IgM, in both moderate and severe patients. Of note, mild patients did not develop ...

Longitudinal analysis reveals that delayed bystander CD8+ T cell ...

The kinetics of the immune changes in COVID-19 across severity groups have not been rigorously assessed. Using immunophenotyping ...

Longitudinal immune dynamics of mild COVID-19 define signatures ...

We deeply profiled the longitudinal immune response in individuals with mild COVID-19 beginning with early time points post-infection (1-15 days) and ...

Immune profiling of COVID-19: preliminary findings and implications ...

SARS-CoV-2 can cause asymptomatic infection in some individuals, mild-to-moderate self-resolving symptoms in others and severe manifestations like acute ...

Longitudinal immune profiling reveals distinct features of COVID-19 ...

Results were stratified based on patient-level data including severity of symptoms and date of reported symptom onset. Findings Longitudinal ...

Longitudinal immune profiling reveals distinct features of COVID-19 ...

Interpretation: This is the first detailed longitudinal analysis of COVID-19 patients of varying severity and outcome, revealing common features ...

immune markers associated with disease severity and resolution

HUMAN ANTIBODY REPERTOIRE IN MILD vs SEVERE COVID-19. ABSTRACT. The authors ... MILD SARS-CoV-2 INFECTION SHOWS HIGHER AFFINITY. MATURATION TO PREFUSION ...