Low dose cisplatin weekly versus high dose cisplatin every ...

Low dose cisplatin weekly versus high dose cisplatin every three ...

Conclusions. Low SMM is predictive for CDLT in HNSCC patients receiving triweekly cisplatin in combination with radiotherapy with curative ...

Low- Versus Standard-Dose Cisplatin for Locally Advanced HNSCC

This trial [JCOG 1008] confirmed beyond doubt that concurrent chemoradiation with weekly cisplatin is noninferior to high-dose cisplatin every 3 ...

Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 ...

Compared with radiotherapy alone, concurrent three-weekly cisplatin resulted in a significantly better larynx preservation, locoregional control, and disease- ...

Comparing High- and Low-Dose Cisplatin for Patients with ...

The Phase II portion of this trial will determine whether radiation therapy combined with weekly low-dose cisplatin is superior to high-dose ...

Once-a-Week Versus Once-Every-3-Weeks Cisplatin ...

In locally advanced head and neck squamous cell carcinoma (LAHNSCC), high-dose (100 mg/m2) once-every-3-weeks cisplatin added to curative ...

Concurrent Chemoradiation Therapy With Weekly Cisplatin for ...

When combined with radiotherapy as definitive treatment of locally advanced head and neck squamous cell carcinoma, cisplatin at a dose of 40 ...

Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose ...

This phase II/III trial compares the effect of the combination of high-dose cisplatin every three weeks and radiation therapy versus low-dose cisplatin weekly ...

Cisplatin Every 3 Weeks Versus Weekly With Definitive Concurrent ...

Alternative dosing of cisplatin has been evaluated, including the use of weekly low-dose cisplatin (LDC, 40 mg/m2 once weekly during ...

High-Dose Three-Weekly or Low-Dose Weekly Cisplatin during ...

In locally advanced squamous cell carcinoma of the head and neck, adding three cycles of high-dose (100 mg/m2) cisplatin every three weeks ...

Standard versus fractionated high-dose cisplatin plus radiation for ...

Chemoradiotherapy with high-dose cisplatin (HD-Cis: 100 mg/m2 q3w for three cycles) is the standard of care (SOC) in locally advanced head and neck squamous ...

Concurrent chemoradiotherapy with cisplatin given once-a-week ...

National Comprehensive Cancer Network (NCCN) guidelines version 2.2022 for head and neck cancers [19] recommends high-dose three-weekly cisplatin as the ...

Three Weekly Versus Weekly Cisplatin: Comparison of two Different ...

Though 3-weekly cisplatin is the recommended schedule, it is associated with severe adverse reactions. A lower dose weekly schedule is generally ...

Standard versus fractionated high-dose cisplatin plus radiation for ...

Thus, the radio- sensitization regimen in the form of weekly administration of 40 mg/m2 cisplatin (Cis-40) for 6 to 7 cycles has been adopted by ...

Weekly versus triweekly cisplatin plus intensity-modulated ...

Radiotherapy quality assurance (QA) was performed before radiation treatment for all the NPC patients. CDDP was initiated on the first day of radiotherapy, and ...

3-weekly or weekly cisplatin concurrently with radiotherapy for ...

The standard regimen includes 3-weekly cisplatin, but weekly regimens are often used to lower toxicity. Reaching a cumulative dose of ≥200 mg/m2 ...

The CISLOW-study protocol | PLOS ONE

(2023) Low dose cisplatin weekly versus high dose cisplatin every three weeks in primary chemoradiotherapy in head and neck cancer patients ...

Comparison of standard-dose 3-weekly cisplatin and low-dose

All patients included in this analysis were initially treated with upfront concurrent chemoradiation therapy using cisplatin dosing schedule of either 100 mg/m ...

Weekly Low-Dose Versus Three-Weekly High-Dose Cisplatin for ...

There was no difference in treatment efficacy as measured by overall survival or response rate between the chemoradiation settings with low-dose weekly and high ...

A comparative study between cisplatin weekly versus every 3 weeks ...

High dose cisplatin concomitantly used with radiotherapy showed higher but insignificant survival in comparison with low dose cisplatin with better toxicity ...

Comparison of daily low dose cisplatin versus weekly cisplatin ...

Chemotherapy compliance (six cycles in weekly or 28–30 cycles in daily cisplatin) were 63% and 73%, respectively. The primary reason for noncompliance toward ...