- Gene ResultLPAR1 lysophosphatidic acid receptor 1 [ 🔍
- Role of lysophosphatidic acid and its receptors in health and disease🔍
- Lpar1 lysophosphatidic acid receptor 1 [ 🔍
- Lysophosphatidic acid receptor 1 🔍
- The Roles of Lpar1 in Central Nervous System Disorders and ...🔍
- LPA 1 receptor🔍
- coupled human lysophosphatidic acid receptor 1 complexed with a ...🔍
- LPA receptor signaling🔍
Lpar1 lysophosphatidic acid receptor 1 [
Gene ResultLPAR1 lysophosphatidic acid receptor 1 [ (human)] - NCBI
The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors.
Lysophosphatidic acid receptor 1 also known as LPA1 is a protein that in humans is encoded by the LPAR1 gene. ... LPA1 is a G protein-coupled receptor that binds ...
Role of lysophosphatidic acid and its receptors in health and disease
Lysophosphatidic acid (1- or 2-acyl-sn-glycerol 3-phosphate/radyl-glycerol-phosphate, LPA) is a bioactive phospholipid that is produced during ...
Lpar1 lysophosphatidic acid receptor 1 [ (house mouse)] - NCBI
Enables PDZ domain binding activity and lysophosphatidic acid receptor activity. Involved in several processes, including adenylate ...
A preclinical in vitro and in vivo study found that antagonizing—or blocking— LPA1 receptors may have an impact in treating lung injury and ...
The Roles of Lpar1 in Central Nervous System Disorders and ...
Lysophosphatidic acid receptor 1 (Lpar1), which is found in almost all human tissues but is most abundant in the brain, can couple to G ...
LPA 1 receptor - IUPHAR/BPS Guide to PHARMACOLOGY
... receptor, 2 | LPA receptor 1 | Lpar1 | lysophosphatidic acid receptor Edg-2. Database Links Click here for help. Specialist databases. GPCRdb, lpar1_human (Hs) ...
coupled human lysophosphatidic acid receptor 1 complexed with a ...
Lysophosphatidic acid receptor 1 (LPA1) is one of the six G protein-coupled receptors activated by the bioactive lipid, lysophosphatidic ...
602282 - LYSOPHOSPHATIDIC ACID RECEPTOR 1; LPAR1 - OMIM
Online Mendelian Inheritance in Man (OMIM) is a comprehensive, authoritative compendium of human genes and genetic phenotypes that is freely available and ...
LPAR1 Gene - Lysophosphatidic Acid Receptor 1 - GeneCards
GeneCards Summary for LPAR1 Gene. LPAR1 (Lysophosphatidic Acid Receptor 1) is a Protein Coding gene. Diseases associated with LPAR1 include Pulmonary Fibrosis ...
LPA receptor signaling: pharmacology, physiology, and ...
Lpar1−/− and maLPA1 ... Stereotyped fetal brain disorganization is induced by hypoxia and requires lysophosphatidic acid receptor 1 (LPA1) signaling.
Lysophosphatidic acid receptor 1 inhibition: a potential treatment ...
Lysophosphatidic acid (LPA)-mediated activation of LPA receptor 1 (LPAR1) contributes to the pathophysiology of fibrotic diseases such as idiopathic ...
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA ...
Here we describe a new series of LPA 1 agonists among which derivative (S)-17 (UCM-05194) stands out as the most potent and selective LPA 1 receptor agonist ...
#Z1300N Lysophosphatidic Acid Receptor 1 | Montana Molecular
Express Human Lysophosphatidic acid receptor 1 (LPAR1) in mammalian cells, packaged in BacMam for consistent expression across a wide range of cell lines and ...
Lysophosphatidic acid receptor 1 (LPA 1 ) plays critical roles in ...
Lysophosphatidic acid receptor 1 (LPA1) is in the spotlight because its synthetic antagonist has been under clinical trials for lung ...
Lpar1 MGI Mouse Gene Detail - lysophosphatidic acid receptor 1
View mouse Lpar1 Chr4:58435255-58553898 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic ...
We demonstrate that genetic ablation of the lysophosphatidic acid receptor 1 (LPAR1) reduces hypertrophy and fibrosis in a mouse model of HCM.
Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor ...
The oxycyclohexyl acid BMS-986278 (33) is a potent lysophosphatidic acid receptor 1 (LPA1) antagonist, with a human LPA1 Kb of 6.9 nM.
Human LPAR1/LPA1/EDG-2 (NP_001392) VersaClone cDNA
... 1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P ...
Human Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit
EDG2; Gpcr26; LPA1; Mrec1.3; edg-2; rec.1.3; vzg-1; Endothelial Differentiation,Lysophosphatidic Acid G-Protein-Coupled Receptor 2 ...
LPAR1
Lysophosphatidic acid receptor 1 also known as LPA₁ is a protein that in humans is encoded by the LPAR1 gene. LPA₁ is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid.