Lysophospholipid

Lysophospholipid - an overview | ScienceDirect Topics

Lysophospholipids are important signaling mediators that exert a wide-range of biological effects. Two well-studied examples are lysophosphatidic acid (LPA) ...

Lysophospholipid - an overview | ScienceDirect Topics

Lysophospholipids (LPLs) are bioactive molecules that possess a large polar or charged head and a single hydrophobic carbon chain.

Lysophospholipid Mediators in Health and Disease - PMC

In this review, we focus on how LPA regulates fibrosis, neuropathic pain, abnormal angiogenesis, endometriosis, and disorders of neuroectodermal development.

Lysophospholipid receptor - Wikipedia

The lysophospholipid receptor (LPL-R) group are members of the G protein-coupled receptor family of integral membrane proteins that are important for lipid ...

Synthesis of Lysophospholipids - PMC

New synthetic methods for the preparation of biologically active phospholipids and lysophospholipids (LPLs) are very important in solving problems of membrane– ...

Lysophospholipids - SpringerLink

Lysophospholipids are auto‐ or paracrine regulators of cell growth and survival, migration and chemotaxis, cytoskeletal architecture, cell–cell‐contacts and ...

Lysophospholipids and Their G-Coupled Protein Signaling in ...

Considerable evidence now demonstrates the crucial role of LPA and S1P in neurodegenerative diseases, especially in Alzheimer's disease (AD).

Lysophospholipid Mediators in Health and Disease - Annual Reviews

Lysophospholipids, exemplified by lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), are produced by the metabolism and ...

Lysophospholipid Signaling | Literature & Media - Cayman Chemical

Lysophospholipid Signaling ... Lysophospholipids (LPA, LysoPS, LPI, S1P) transduce signals through their specific GPCRs, which activate heterotrimeric G proteins ...

Discovery of a lysophospholipid acyltransferase family essential for ...

We describe a putative enzyme superfamily consisting mainly of three gene families, which catalyzes the transfer of acyl-CoAs to lysophospholipids.

Blood-derived lysophospholipid sustains hepatic phospholipids and ...

This study revealed that PUFA-containing LPCs drive hepatic lipid droplet formation, suppress lipogenesis, and sustain hepatic phospholipid pools.

QuickGO::Term GO:0051978

Enables the directed movement of lysophospholipids into, out of, within or between cells. A lysophospholipid is a phospholipid that lacks one of its fatty acyl ...

Lysophospholipid Receptors: Signaling and Biology - Annual Reviews

Abstract Lysophospholipids (LPs), such as lysophosphatidic acid and sphingosine 1-phosphate, are membrane-derived bioactive lipid mediators.

Lysophospholipid signaling in the function and pathology of the ...

This review will briefly introduce receptor-mediated LP signaling and comprehensively update the physiological and pathological functions of LP signaling in ...

The Many Roles of Lysophospholipid Mediators and ... - J-Stage

This review focuses on identifying the functions of the receptors, enzymes, transporters, and carrier proteins required for these four lysophospholipids to ...

Lysophospholipids - Sigma-Aldrich

Find lysophospholipids and related products for scientific research at Merck.

Lysophospholipid remodeling mediated by the LplT and Aas protein ...

We report that LplT and Aas form a membrane protein complex in E. coli which allows these two enzymes to cooperate efficiently to move lysophospholipids across ...

Lysophospholipid Mediators: Their Receptors and Synthetic Pathways

Lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G protein-coupled receptors (GPCRs).

Lysophospholipid (LPA) receptors | Introduction

Useful general overviews on the nomenclature and introductory notes on the pharmacological characteristics of the lysophospholipid family of receptors.

Lysophospholipid Acyltransferases Mediate Phosphatidylcholine ...

A model for acyl-chain diversification in phosphatidylcholine (PC) is proposed. Lysophospholipid acyltransferases of different pathways regulate PC composition.