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MHC genotyping of non|model organisms using next|generation ...


MHC genotyping of non-model organisms using next-generation ...

The Major Histocompatibility Complex (MHC) is the most important genetic marker to study patterns of adaptive genetic variation determining ...

a new methodology to deal with artefacts and allelic dropout - PubMed

MHC genotyping of non-model organisms using next-generation sequencing: a new methodology to deal with artefacts and allelic dropout · Abstract · Publication ...

A new hybrid approach for MHC genotyping: high-throughput NGS ...

A new hybrid approach for MHC genotyping: high-throughput NGS and long read MinION nanopore sequencing, with application to the non-model ...

Improved high‐throughput MHC typing for non‐model species using ...

Despite the recent expansion in next‐generation sequencing methods, Sanger sequencing (cycle sequencing) remains the most commonly used MHC typing method (43% ...

A New Method for Genotyping MHC Loci Using Next-Generation ...

Given these challenges, sequencing MHC loci in non-model organisms has, until recently, been accomplished by 1) extensive bacterial cloning and direct ...

MHC genotyping of non-model organisms using next-generation ...

Title. MHC genotyping of non-model organisms using next-generation sequencing: a new methodology to deal with artefacts and allelic dropout. Authors ...

MHCtools – an R package for MHC high‐throughput sequencing ...

While several protocols have been developed for MHC genotyping, there is a lack of transparent and standardized tools for downstream analysis of ...

Next-generation genotyping of hypervariable loci in many ...

We demonstrate the utility of using NGS to genotype non-model organisms at complex hypervariable loci like those of the MHC and we validate the ...

Methods for MHC genotyping in non‐model vertebrates | Semantic ...

1 Excerpt. MHC genotyping of non-model organisms using next-generation sequencing: a new methodology to deal with artefacts and allelic dropout · S. SommerA ...

Next-generation genotyping of hypervariable loci in many ...

Quantifying MHC diversity within non-model species is the first step to assessing the relationship of genetic diversity at functional loci to individual fitness ...

Performance Comparison of Different Approaches in Genotyping ...

Newly developed genotyping methods, which rely on the use of next-generation sequencing (NGS), are gradually replacing traditional cloning and Sanger sequencing ...

Intronic primers reveal unexpectedly high major histocompatibility ...

Relatively few studies of non-model organisms have combined MHC sequencing with the genotyping of genome-wide distributed, selectively neutral ...

MHC Genotyping in Human and Nonhuman Species by PCR-based ...

MHC genotyping of non-model organisms using next-generation sequencing: a new methodology to deal with artefacts and allelic dropout. BMC Genomics. 2013;14 ...

State-of-the-art genome inference in the human MHC - ScienceDirect

Array-based SNP (single nucleotide polymorphism) genotyping has been applied to millions of human samples and remains popular for large biobanking and genome- ...

Large-scale MHC class II genotyping of a wild lemur population by ...

The second exons from MHC-DRB and -DQB of 772 and 672 individuals were sequenced, respectively, using a 454 sequencing platform, generating more ...

MHC Genotyping by SSCP and Amplicon-Based NGS Approach in ...

Here, we compared the performance of traditional and next-generation sequencing on genotyping of the major histocompatibility complex genes in chamois.

MHC Genotyping in Human and Nonhuman Species by PCR-based ...

Recently, genotyping of the polymorphisms of MHC genes using targeted next-generation sequencing (NGS) technologies was developed for humans and ...

Low Major Histocompatibility Complex Class I (MHC I) Variation in ...

Genotype frequencies conformed to Hardy–Weinberg expectations, and no signatures of selection in contemporary populations but strong signatures of historical ...

MHC genotyping of non-model organisms using next-generation ...

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MHC Genotyping by SSCP and Amplicon-Based NGS Approach in ...

MHC genotyping of non-model organisms using next-generation sequencing: A new methodology to deal with artefacts and allelic dropout. BMC Genomics, 14 ...