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MS treatment de|escalation


MS treatment de-escalation: review and commentary - PubMed

Almost all currently licensed disease-modifying therapies (DMTs) for MS treatment require prolonged if not lifelong administration.

Retrospectively Exploring De-Escalation of Multiple Sclerosis ...

One area of interest is de-escalation, which involves transitioning patients from high or moderate efficacy disease-modifying therapies (DMTs) ...

Escalation vs. Early Intense Therapy in Multiple Sclerosis - PMC

“Early intense therapy” strategy refers to starting treatment with drugs of higher efficacy from the beginning, despite having a less favorable side-effect ...

Treating Early Relapsing Multiple Sclerosis: Induction & Escalation ...

There are 2 general approaches for the initial treatment of relapsing MS: the escalation approach and the induction approach.

the TREAT-MS Study | PCORI

In the early stages of MS, patients may take standard, first-line medicines to prevent relapses. Some aggressive medicines work better than first-line medicine ...

MS Treatment De-Escalation - YouTube

May people believe stronger MS medications are better despite the increased risks. But should you take them long term?

De-escalation of Disease-Modifying Therapy for People with ...

Introduction. Switching disease-modifying therapy (DMT) may be considered for relapsing–remitting multiple sclerosis (RRMS) if a patient's ...

Bridging the Gap, De-Escalation of MS Disease Modifying Therapies

Although there is a variety of practices using DMTs, there is a lack of universal guidelines for providers on how to use them effectively. 1 One ...

Treatment Escalation vs Immediate Initiation of Highly Effective ...

Findings In this cohort study comparing patients in the Danish and Swedish multiple sclerosis registries, the use of highly effective disease- ...

Escalation Versus Induction/High-Efficacy Treatment Strategies for ...

Alemtuzumab should be considered for induction therapy in MS, as it is more effective than interferon-beta in patients with early active RRMS.

Discontinuing Disease-Modifying Therapies in Multiple Sclerosis

De-escalation refers to use of DMTs when they are most needed and beneficial, with acceptable risks, and subsequent changes to less potent DMTs as MS disease ...

Early intensive MS treatment versus escalation approach

Pietro Iaffaldano, MD, The University of Bari Aldo Moro, Bari, Italy, discusses the results of a research project investigating two ...

Evolution of Disease Modifying Therapy Benefits and Risks - Frontiers

Proponents of an escalation strategy in MS argue that disease activity can be detected early enough for treatment to be effectively escalated and that any ...

Treatment Escalation and De-Escalation in Late-Onset MS

Results from the DISCOMS study suggested that it is probably safe to de-escalate therapy in a population of patients with a median age of 62 ...

Escalation vs Early Aggressive Treatment in Multiple Sclerosis

With early aggressive treatment, the goal is to suppress disease activity early on to prevent the accumulation of disability and the conversion of RRMS to SPMS, ...

De-Escalation of Anti-CD20 Monoclonal Antibodies to Low ...

Anti-CD20 are among the high-efficacy DMTs commonly used in the treatment of multiple sclerosis (MS). Long-term safety data on anti-CD20s are limited ...

(PDF) MS treatment de-escalation: review and commentary

DMT de-escalation or discontinuation in MS patients older than 55 years may be non-inferior to continued treatment with immunosuppressive agents ...

Webinar Highlights: De-escalation and Discontinuation of DMTs

Finally, an important topic to consider is managing the anxiety of individuals with MS and neurologists who intend to stop treatment. A survey ...

De-Escalation of Disease-Modifying Therapy in MS - PracticeUpdate

De-escalation—that is, transitioning patients from high-efficacy therapies with greater risk to safer lower-efficacy therapies—may be ...

Treatments & Medications for MS - National MS Society

MS hug (dysesthesia) · Relaxation techniques and meditation · Loose clothing · Warm compresses · Exercises such as walking, stretching, yoga or gentle swimming ...