MVP study identifies genes linked to re|experiencing symptoms in ...

MVP study identifies genes linked to re-experiencing symptoms in ...

A VA Million Veteran Program study has identified multiple locations in the human genome related to the risk of re-experiencing traumatic ...

Genetic basis for re-experiencing symptoms in PTSD | ScienceDaily

A study has identified multiple locations in the human genome related ... genetic and health record data available through MVP, the research ...

MVP study reveals new markers of genetic risk for PTSD

A large VA Million Veteran Program study found new genetic markers for posttraumatic stress disorder risk. The researchers identified 18 ...

Genome-wide Association Study of Posttraumatic Stress Disorder ...

The probability to observe concordant direction of all eight MVP-identified loci in UKB GWAS by chance is 0.4%. The whole-genome polygenic risk ...

Genes Associated With PTSD's Re-experiencing Symptoms Found

The researchers compared the genomes of 146,660 white veterans and 19,983 black veterans who had volunteered for MVP. Of the eight genomic ...

Genome-wide association analyses of posttraumatic stress disorder ...

In our previous study of intrusive re-experiencing symptoms in MVP ... Genomewide association study identifies 30 loci associated with ...

International meta-analysis of PTSD genome-wide association ...

Finally, we demonstrate that polygenic risk for PTSD is significantly predictive of re-experiencing symptoms in the Million Veteran Program ...

Robust Findings From 25 Years of PTSD Genetics Research

An extended locus on chromosome 17 was also identified, with lead SNP rs2532252 (p = 4.5 × 10−10) closest to the KANSL1 gene (KAT8 regulatory ...

Reproducible Genetic Risk Loci for Anxiety - Psychiatry Online

The authors identified novel genome-wide significant associations near genes involved with global regulation of gene expression (SATB1) and the ...

Genomic risk for post-traumatic stress disorder in families densely ...

... associated with PTSD re-experiencing symptoms in the MVP [10]. The ... study of alcohol-dependence symptom counts in extended pedigrees identifies ...

Posttraumatic stress disorder: from gene discovery to disease biology

Genetic studies based on such wide screening can uncover loci in molecular pathways that were not previously expected to be associated with PTSD ...

Gene Expression Analysis in Three Posttraumatic Stress Disorder ...

Co-expression analysis identified four modules of genes associated with ... It is characterized by re-experiencing symptoms, avoidance, and persistent ...

Genetic mechanisms underlying arrhythmogenic mitral valve prolapse

MVP with or without mitral regurgitation can be associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD). Research on ...

Mitral Valve Prolapse and Its Motley Crew‐Syndromic Prevalence ...

MVP has been identified as a component of many genetic syndromes, and genome‐wide association studies have identified primary loci thought to be ...

From genetics to systems biology of stress-related mental disorders

A closer examination of the hits identified from this GWAS showed that 34 of the significant genes have immune-related function (Tubbs et al., 2020). The ...

Genetics of mitral valve prolapse and its clinical impact

However, this association of MVP with sudden cardiac death (SCD) may in part be due to ascertainment bias. More recent data have identified a ...

Researchers Identify Novel Genetic Variants Linked to Type-2 ...

Crescenz Veterans Affairs Medical Center (CMCVAMC) found hundreds of genetic variants never before linked to the disease. The study also ...

Diversity and scale: Genetic architecture of 2068 traits in ... - Science

Leveraging dense MVP data, we conducted GWASs across 2068 traits in four population groups based on genetic similarity to AFR, AMR, EAS, and ...

A Locus for Autosomal Dominant Mitral Valve Prolapse ... - Cell Press

MVP is genetically heterogeneous and is inherited as an autosomal dominant trait that exhibits both sex- and age-dependant penetrance. In this report, we ...

Genetics & Parkinson's

Genetic testing is currently available for the following genes related to Parkinson's: GBA, LRRK2, PRKN, SNCA, PINK1, PARK7 and VPS35. Am I more likely to get ...