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Maintenance of a short|lived protein required for long|term memory ...


Maintenance of a short-lived protein required for long-term memory ...

Activity-dependent expression of immediate early genes (IEGs) is critical for long-term synaptic remodeling and memory.

Maintenance of a short-lived protein required for long-term memory ...

Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation. Graphical abstract.

Short-lived Molecules Support Long-term Memory - The Scientist

“It's been a long-held dogma in the field that protein synthesis is a necessary molecular substrate for memory consolidation,” said Stony Brook ...

Einstein Researchers Discover How Long-Lasting Memories Form ...

The paper is titled “Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation.

Protein degradation and protein synthesis in long-term memory ...

These results indicate that new protein synthesis is a necessary step in the transfer of a retrieved memory back to long-term storage, suggesting that both the ...

Maintenance of a short-lived protein required for long-term memory ...

Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation.

How do mRNAs maintain protein levels for long term memory?

Strengthening the neuronal connections requires new proteins to be made at the synapses and maintained over time. Since proteins are made from ...

Persistence of Long-Term Memory Storage Requires a Late Protein ...

The main finding of this work is that protein synthesis and BDNF in the rat hippocampus are required during a restricted time window around 12 ...

Unraveling the Genetic Mechanisms Behind Long-Lasting Memories ...

Proteins are needed to stabilize the long-lasting synaptic connections required for long-term memories. The blueprints for those proteins are ...

Long-term Memories Are Maintained by Prion-like Proteins

Kandel first identified functional prions in the giant sea slug (Aplysia) and found they contribute to the maintenance of memory storage. More ...

Environmental Light Is Required for Maintenance of Long-Term ...

SIGNIFICANCE STATEMENT Temporary memory can be consolidated into long-term memory (LTM) through de novo protein synthesis and functional ...

Defying Dogma: Decentralized Translation in Neurons - The Scientist

In the 1960s, scientists studying memory formation in goldfish and rodents demonstrated that long-term but not short-term storage of memories ...

Identification of long-lived synaptic proteins by proteomic analysis of ...

Earlier studies have suggested that synaptic kinases can mediate the long-term maintenance of plasticity and memory. For example, activation of ...

Neuron, Volume 111

Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation. Sulagna Das, Pablo J. Lituma ...

Long-term memory consolidation: The role of RNA-binding proteins ...

1. The proteins themselves are required for long-term memory formation or its neurophysiological correlates like LTF. 2. In yeast cells, cultured cells and ...

Role of protein synthesis and DNA methylation in the consolidation ...

The formation of long-term memory depends on new proteins being made in the brain. These new proteins are used partly to build the new ...

How long-lasting memories form in the brain | ScienceDaily

Sulagna Das, Pablo J. Lituma, Pablo E. Castillo, Robert H. Singer. Maintenance of a short-lived protein required for long-term memory involves ...

The molecular biology of memory: cAMP, PKA, CRE, CREB-1 ...

In both, short-term memory involves covalent modification of preexisting proteins and changes in the strength of preexisting synaptic ...

Identification of long-lived synaptic proteins by proteomic ... - PNAS

tremely long-lived proteins (LLPs) may reside at synapses and form part of the molecular basis for long-term memory maintenance. Previous ...

Consolidation and maintenance of Drosophila long-term memory ...

These results suggest that Ap in l-LNvs is necessary for memory consolidation. Thus, we examined when ap in Pdf neurons is required during ...