Manipulation of Long Non|coding RNAs in Cardiovascular Disease ...

Manipulation of Long Non-coding RNAs in Cardiovascular Disease ...

This chapter provides an overview on lncRNAs in cardiovascular diseases (CVDs) and specifically highlights tools used for loss-of-function studies.

The Role of Long Non-Coding RNAs in Cardiovascular Diseases

Long non-coding RNAs are dysregulated in the development and progression of various CVDs, such as atherosclerosis, myocardial infarction, ...

Long Non-Coding RNAs in Cardiovascular Diseases

lncRNAs are differentially expressed in cardiovascular diseases such as heart failure, myocardial infarction, coronary artery disease, and arterial hypertension ...

Noncoding RNAs in Cardiovascular Disease: Current Knowledge ...

Similarly, the identification of long noncoding RNAs that appear to play an important role in cardiovascular disease processes, coupled with the ...

Regulation of Long Non-coding RNAs and MicroRNAs in Heart ...

Increasing evidence has detailed the importance of these non-coding RNAs, both individually and in an axis of regulation, in the processes and diseases ...

The Function and Therapeutic Potential of Long Non-coding RNAs ...

lncRNAs are a heterogeneous group of transcripts exerting major regulatory roles in gene expression, and their importance in cardiovascular disease has been ...

Long Noncoding RNAs in Cardiovascular Diseases

Several lncRNAs are regulated during acute myocardial infarction (eg, Novlnc6) and heart failure (eg, Mhrt), whereas others control hypertrophy, ...

The Emerging Role of Long Non-coding RNAs and Circular RNAs in ...

LncRNAs can affect CAD pathogenesis through regulation of immune responses, modulation of function of endothelial cells and vascular smooth muscles, and ...

Regulatory mechanisms of long non-coding RNAs on mitochondrial ...

Long non-coding RNAs (lncRNAs) possess the ability to influence the pathophysiological mechanisms underlying cardiac disease through their regulation of gene ...

The role and medical prospects of long non-coding RNAs in ...

It has been reported that lncRNAs regulate gene action during cardiovascular disease (CVD) and cardiac development. Examining how lncRNAs are ...

Dysregulated micro-RNAs and long noncoding RNAs in cardiac ...

Micro-RNAs and long noncoding RNAs (lncRNAs) are the best characterized ncRNAs. These ncRNAs can have profound effects on the regulation of gene ...

Roles of long noncoding RNAs in human inflammatory diseases

Atherosclerosis and coronary artery disease (CAD) are primary inflammatory cardiovascular diseases that have a significant impact on the global ...

Long Non-Coding RNAs (lncRNAs) in Heart Failure - MDPI

Initially disregarded as mere transcriptional background noise, lncRNAs have now emerged as pivotal regulators of gene expression and cellular processes. They ...

Non-coding RNA in cardiovascular disease: a general overview on ...

The present review discusses how ncRNAs [including microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs)] are involved ...

Single-cell transcriptional landscape of long non-coding RNAs ...

Long non-coding RNAs (lncRNAs) comprise the most representative transcriptional units of the mammalian genome. They are associated with ...

Clinical Significance of MicroRNAs, Long Non-Coding RNAs ... - MDPI

... manipulation of non ... The Biological Function and Potential Mechanism of Long Non-coding RNAs in Cardiovascular Disease.

Long noncoding RNA in cardiac aging and disease - Oxford Academic

New therapies, especially in the elderly, are needed to combat CVD. This review is focused on the role of long noncoding RNA (lncRNA) in CVD.

[PDF] Non-coding RNAs in cardiovascular diseases: diagnostic and ...

An update on recent developments and perspectives for diagnostic and therapeutic use of ncRNAs in cardiovascular diseases, ...

Long Noncoding RNA: a New Player of Heart Failure?

Not surprisingly, ncRNAs are emerging as important players in several human pathologies, including cardiovascular diseases [6–9]. Indeed, miRNAs ...

Long Non-Coding RNAs in Cardiovascular Diseases - ResearchGate

This class of non-coding RNAs is related to the pathophysiology of the cardiovascular system. The different expression profiles of lncRNAs, in ...