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Mapping human monoclonal IgE epitopes on the major dust mite ...


Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

IgE Abs drive the symptoms of allergic disease upon cross-linking allergens on mast cells or basophils. If the IgE binding sites on the ...

Mapping human monoclonal IgE epitopes on the major dust mite ...

The overlap of the three human IgE mAb epitopes could indicate that the area recognized by these antibodies is immunodominant for Der p 2. Two of the IgE mAb ( ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

To our knowledge, this study presents the first epitope mapping of four human monoclonal IgE Abs to Der p 2. This is one of the most important allergens ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

A new hybridoma technology using human B cells from house dust mite–allergic patients was used to identify four Der p 2–specific hIgE mAbs. Their relative ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2. by Geoffrey A Mueller, Jill Glesner, Jacob L Daniel, Jian Zhang, Noah Hyduke, ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

Abstract IgE Abs drive the symptoms of allergic disease upon cross-linking allergens on mast cells or basophils. If the IgE binding sites on the allergens ...

Structural analysis of human IgE monoclonal antibody epitopes on ...

19. Mueller, G.A. ∙ Glesner, J. ∙ Daniel, J.L. ... Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2. J Immunol. 2020; 205:1999 ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2. Ontology highlight. ABSTRACT: IgE Abs drive the symptoms of allergic disease ...

and C-terminal sequences required to bind human IgE of the major ...

Determination of the N- and C-terminal sequences required to bind human IgE of the major house dust mite allergen Der f 2 and epitope mapping for monoclonal ...

Human IgE monoclonal antibody recognition of mite allergen Der p ...

, et al. 2020 . Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2 . J Immunol . 205. : 1999. –. 2007 . Google Scholar · Crossref.

Determination of immunogenic epitopes in major house dust mite ...

48. Mueller, GA ∙ Glesner, J ∙ Daniel, JL ... Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2. J Immunol ...

Conformational IgE Epitope Mapping of Der p 2 and the Evaluations ...

The crystal structure of a major dust mite allergen Der p 2, and its biological implications. ... Human Monoclonal IgE Antibodies—a Major ...

Structural analysis of human IgE monoclonal antibody epitopes on ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2. Mueller, Geoffrey A.; Glesner, Jill; Daniel, Jacob L. The Journal of ...

Human Monoclonal IgE Antibodies—a Major Milestone in Allergy

... human chimeric IgE monoclonal antibody to the house dust mite ... Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2.

Human IgE monoclonal antibody recognition of mite allergen Der p ...

X-ray crystal structure analyses revealed an important conformational epitope associated with the IgE antibody repertoire to a major mite allergen, ...

Epitope Structural Analysis of Dust Mite Allergen Der p 2 with ...

Human IgE monoclonal antibodies (hIgE mAb) against Der p 2 have been developed using human hybridoma technology, which contain the natural pairing of heavy and ...

Structural Analysis of Human IgE Monoclonal Antibody Epitopes on ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2. Article. Full-text available. Sep 2020; J IMMUNOL.

Human Monoclonal IgE Antibodies—a Major Milestone in Allergy

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2. Mueller, Geoffrey A.; Glesner, Jill; Daniel, Jacob L. The ...

The Potential of Human Monoclonal IgE Antibodies to Establish ...

... IgE from allergic subjects and extensive epitope mapping of major allergenic proteins. ... dust mite allergen [6]. In the US, the US Food ...

Structural Aspects of the Allergen-Antibody Interaction - Frontiers

... human IgE monoclonal antibodies, ideal for epitope mapping. The ... Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2.